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How are genes and DNA related to psoriasis?

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When you have psoriasis, the genes that control your immune system signals get mixed up. Instead of protecting your body from invaders as it's designed to do, it promotes inflammation and turns skin cells on overdrive. About 10 in every 100 people have genes that make them more likely to get psoriasis, but only 2 or 3 of them actually get it.

SOURCES:

National Psoriasis Foundation: "Psoriasis Causes and Known Triggers," "Genes and Psoriasis," "Stress," "How Cigarettes and Alcohol Affect Psoriasis," "Pregnancy and Nursing."

NHS Choices: "Psoriasis - Causes."

Medscape: "Dermatological Management of Human Immunodeficiency Virus (HIV)."

American Osteopathic College of Dermatology: "Palmoplantar Pustulosis."

Ceovic, R. BioMed Research International, 2013.

Reviewed by Brunilda Nazario on August 24, 2020

SOURCES:

National Psoriasis Foundation: "Psoriasis Causes and Known Triggers," "Genes and Psoriasis," "Stress," "How Cigarettes and Alcohol Affect Psoriasis," "Pregnancy and Nursing."

NHS Choices: "Psoriasis - Causes."

Medscape: "Dermatological Management of Human Immunodeficiency Virus (HIV)."

American Osteopathic College of Dermatology: "Palmoplantar Pustulosis."

Ceovic, R. BioMed Research International, 2013.

Reviewed by Brunilda Nazario on August 24, 2020

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Can certain genes trigger a psoriasis flare?

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