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How do biologics treat psoriasis?

ANSWER

Biologics target proteins in your immune system that play a role in the inflammation process. They have fewer side effects than traditional systemic therapy. The biologics now available to treat plaque psoriasis and psoriatic arthritis are:

  • Adalimumab (Humira)
  • Etanercept (Enbrel)
  • Infliximab (Remicade)
  • Secukinumab (Cosentyx)
  • Ustekinumab (Stelara)

SOURCES:

Abel, E. "Psoriasis," , BC Decker, 2005. ACP Medicine

American Academy of Dermatology.

American College of Rheumatology: "Psoriatic Arthritis."

FDA. "FDA approves new psoriasis drug Taltz," “FDA approves Inflectra, a biosimilar to Remicade,” “FDA approves Amjevita, a biosimilar to Humira.”

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

Medscape: "FDA OKs Biologic Guselkumab (Tremfya) for Plaque Psoriasis."

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

Strober, Bruce E., MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to NexGenix Pharmaceuticals Holdings, Amgen, Biogen, Genentech, Fujisawa, and 3M.

Reviewed by Stephanie S. Gardner on July 17, 2019

SOURCES:

Abel, E. "Psoriasis," , BC Decker, 2005. ACP Medicine

American Academy of Dermatology.

American College of Rheumatology: "Psoriatic Arthritis."

FDA. "FDA approves new psoriasis drug Taltz," “FDA approves Inflectra, a biosimilar to Remicade,” “FDA approves Amjevita, a biosimilar to Humira.”

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

Medscape: "FDA OKs Biologic Guselkumab (Tremfya) for Plaque Psoriasis."

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

Strober, Bruce E., MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to NexGenix Pharmaceuticals Holdings, Amgen, Biogen, Genentech, Fujisawa, and 3M.

Reviewed by Stephanie S. Gardner on July 17, 2019

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Which biologics are approved for psoriasis?

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