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How does Hydroxyurea treat psoriasis?

ANSWER

Hydroxyurea (Hydrea) is a psoriasis drug that has fewer side effects than some of the stronger systemic medications, but is also less effective.

It can cause bone marrow problems and a higher chance of skin cancer. Don't take it if you're pregnant or might become pregnant.

While it's been given as a psoriasis treatment for years, the FDA has not specifically approved it for this use.

SOURCES:

Abel, E. "Psoriasis," , BC Decker, 2005. ACP Medicine

American Academy of Dermatology.

American College of Rheumatology: "Psoriatic Arthritis."

FDA. "FDA approves new psoriasis drug Taltz," “FDA approves Inflectra, a biosimilar to Remicade,” “FDA approves Amjevita, a biosimilar to Humira.”

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

Medscape: "FDA OKs Biologic Guselkumab (Tremfya) for Plaque Psoriasis."

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

Strober, Bruce E., MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to NexGenix Pharmaceuticals Holdings, Amgen, Biogen, Genentech, Fujisawa, and 3M.

Reviewed by Stephanie S. Gardner on July 17, 2019

SOURCES:

Abel, E. "Psoriasis," , BC Decker, 2005. ACP Medicine

American Academy of Dermatology.

American College of Rheumatology: "Psoriatic Arthritis."

FDA. "FDA approves new psoriasis drug Taltz," “FDA approves Inflectra, a biosimilar to Remicade,” “FDA approves Amjevita, a biosimilar to Humira.”

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

Medscape: "FDA OKs Biologic Guselkumab (Tremfya) for Plaque Psoriasis."

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

Strober, Bruce E., MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to NexGenix Pharmaceuticals Holdings, Amgen, Biogen, Genentech, Fujisawa, and 3M.

Reviewed by Stephanie S. Gardner on July 17, 2019

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How does Methotrexate treat psoriasis?

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