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How does pimecrolimus (Elidel), tacrolimus (Protopic), and crisaborole (Eucrisa) treat psoriasis?

ANSWER

Pimecrolimus (Elidel), tacrolimus (Protopic), and crisaborole (Eucrisa) can help stop inflammation. Your doctor may call these drugs "calcineurin inhibitors." They're sometimes used to treat psoriasis when other medications don't work.

Talk to your doctor before taking these medications, and read the FDA black box warning on the label: There may be a link between these drugs and certain cancers.

SOURCES: 

Bruce E. Strober, MD, PhD, associate director of dermatopharmacology, department of dermatology, New York University School of Medicine; co-director, Psoriasis and Psoriatic Arthritis Center; consultant for Amgen, Biogen, Genentech, Fujisawa, and 3M.

Jeffrey M. Weinberg, MD, director of the Clinical Research Center, St. Luke's-Roosevelt Hospital Center, New York City; assistant clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant for Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

American Academy of Dermatology.

American Academy of Dermatology, PsoriasisNet.

National Psoriasis Foundation.

Abel, E. "Dermatology III: Psoriasis," ACP Medicine, April 2005.

Reviewed by Stephanie S. Gardner on July 17, 2019

SOURCES: 

Bruce E. Strober, MD, PhD, associate director of dermatopharmacology, department of dermatology, New York University School of Medicine; co-director, Psoriasis and Psoriatic Arthritis Center; consultant for Amgen, Biogen, Genentech, Fujisawa, and 3M.

Jeffrey M. Weinberg, MD, director of the Clinical Research Center, St. Luke's-Roosevelt Hospital Center, New York City; assistant clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant for Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

American Academy of Dermatology.

American Academy of Dermatology, PsoriasisNet.

National Psoriasis Foundation.

Abel, E. "Dermatology III: Psoriasis," ACP Medicine, April 2005.

Reviewed by Stephanie S. Gardner on July 17, 2019

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What is the emotional toll of psoriasis?

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