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What are some biologic medicines that treat moderate to severe psoriasis?

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Biologic medicines approved by the FDA to treat moderate to severe psoriasis include:

Biologics work well for treating psoriasis. In clinical trials, each of the drugs lowered psoriasis activity by at least 75% in many people.

  • Adalimumab (Humira), a TNF-alpha-blocking antibody
  • Adalimumab-atto (Amjevita), a biosimilar (duplicate) to Humira
  • Brodalumab (Siliq), a human antibody against interleukins
  • Etanercept (Enbrel), a TNF-alpha blocker
  • Etanercept-szzs (Erelzi), a TNF-alpha blocker
  • Infliximab (Remicade), a TNF-alpha blocker
  • Ixekizumab (Taltz), an antibody that binds to inflammation-causing proteins/interleukins
  • Secukinumab (Cosentyx), a human antibody against interleukins
  • Ustekinumab (Stelara), a human antibody against interleukins

From: The Latest in Psoriasis Treatment WebMD Medical Reference

SOURCES:

Callen, J.P.,   2003; vol 49: pp 351-356. Journal of the American Academy of Dermatology,

FDA: "FDA approves new psoriasis drug Taltz."

News release, FDA: "FDA approves Amjevita, a biosimilar to Humira." 

Lebwohl, M.,   2003; vol 49: pp S118-S124. Journal of the American Academy of Dermatology,

Lowes, M.A.,  , 2007; vol 445: pp 866-873. Nature

Nickoloff, B.J.,   2004; vol 113: pp 1664-1675. Journal of Clinical Investigation,

Saini, R.,   2005; vol 11: pp 273-280. Current Pharmaceutical Design,

Reviewed by Debra Jaliman on November 30, 2018

SOURCES:

Callen, J.P.,   2003; vol 49: pp 351-356. Journal of the American Academy of Dermatology,

FDA: "FDA approves new psoriasis drug Taltz."

News release, FDA: "FDA approves Amjevita, a biosimilar to Humira." 

Lebwohl, M.,   2003; vol 49: pp S118-S124. Journal of the American Academy of Dermatology,

Lowes, M.A.,  , 2007; vol 445: pp 866-873. Nature

Nickoloff, B.J.,   2004; vol 113: pp 1664-1675. Journal of Clinical Investigation,

Saini, R.,   2005; vol 11: pp 273-280. Current Pharmaceutical Design,

Reviewed by Debra Jaliman on November 30, 2018

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