PREVIOUS QUESTION:

 

NEXT QUESTION:

 

What biologic drugs are used to treat moderate to severe psoriasis?

ANSWER

Biologic drugs include:

  • Ixekizumab (Taltz) and secukinumab (Cosentyx): These are antibodies that bind to interleukin-17A, a protein that is involved in inflammation.
  • Tumor necrosis factor-alpha blockers, including adalimumab (Humira); adalimumab-atto (Amjevita), a biosimilar to Humira; etanercept (Enbrel); etanercept-szzs (Erelzi), a biosimilar to Enbrel; and infliximab (Remicade). These drugs block a chemical messenger of the immune system called TNF-alpha. People with psoriasis have too much of this substance, which causes inflammation.
  • Ustekinumab (Stelara): This drug blocks cytokines in the body called interleukin-12 and interleukin-23, which are thought to promote the increased growth rate of skin cells and inflammation from psoriasis.

SOURCES:

American Academy of Dermatology. Bhosle, M. , June 2006. FDA. "FDA approves new psoriasis drug Taltz." “FDA approves Amjevita, a biosimilar to Humira. Medscape: "FDA OKs Biologic Guselkumab (Tremfya) for Plaque Psoriasis." National Psoriasis Foundation.




Health and Quality of Life Outcomes

Reviewed by Debra Jaliman on June 25, 2019

SOURCES:

American Academy of Dermatology. Bhosle, M. , June 2006. FDA. "FDA approves new psoriasis drug Taltz." “FDA approves Amjevita, a biosimilar to Humira. Medscape: "FDA OKs Biologic Guselkumab (Tremfya) for Plaque Psoriasis." National Psoriasis Foundation.




Health and Quality of Life Outcomes

Reviewed by Debra Jaliman on June 25, 2019

NEXT QUESTION:

What are the side effects of biologic treatments for moderate to severe psoriasis?

WAS THIS ANSWER HELPFUL

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.

    Other Answers On: