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What causes palmoplantar pustulosis (PPP)?

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The cause is unclear, but there's a known link between palmoplantar pustulosis (PPP) and smoking. Studies show that up to 90% of people with the skin condition smoke or once did.

Nicotine in tobacco products can affect your skin cells and cause inflammation in your sweat glands, especially on your hands and feet. If you stop smoking, your symptoms may get better.

SOURCES:

American Osteopathic College of Dermatology: "Palmoplantar Pustulosis."

British Association of Dermatologists: "Palmoplantar Pustulosis."

Canadian Medical Association: "Palmoplantar pustulosis."

Mayo Clinic: "Psoriasis."

Melwani, P. November 2009. JAMA Dermatology,

National Center for Biotechnology Information: "Rapid Improvement of Palmoplantar Psoriasis after Cessation of Smoking."

National Psoriasis Foundation: "Phototherapy."

UpToDate: "Palmoplantar pustulosis: Treatment."

Reviewed by Debra Jaliman on November 13, 2018

SOURCES:

American Osteopathic College of Dermatology: "Palmoplantar Pustulosis."

British Association of Dermatologists: "Palmoplantar Pustulosis."

Canadian Medical Association: "Palmoplantar pustulosis."

Mayo Clinic: "Psoriasis."

Melwani, P. November 2009. JAMA Dermatology,

National Center for Biotechnology Information: "Rapid Improvement of Palmoplantar Psoriasis after Cessation of Smoking."

National Psoriasis Foundation: "Phototherapy."

UpToDate: "Palmoplantar pustulosis: Treatment."

Reviewed by Debra Jaliman on November 13, 2018

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Who can get palmoplantar pustulosis (PPP)?

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