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What is brodalumab (Siliq)?

ANSWER

Brodalumab (Siliq) is a biologic used for the treatment of plaque psoriasis. This medicine comes as a prefilled syringe that gets injected under your skin. Your doctor generally gives you the shot in his or her office. The medicine's label has an FDA warning that some people who take brodalumab may have a greater chance of having thoughts and actions of suicide. So the FDA suggests doctors weigh the risks and benefits of the medicine before suggesting it for people who have had depression or suicidal thoughts in the past. The drug also has a risk of infections.

SOURCES:

Abel, E. "Psoriasis," ACP Medicine, BC Decker, 2005.

American Academy of Dermatology.

Amgen Prescribing Information, Amjevita.

Bruce E. Strober, MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to Amgen, Biogen, Genentech, Fujisawa, NexGenix Pharmaceuticals Holdings Inc. and 3M.

Coxentyx.com. 

FDA: "FDA approves new psoriasis drug Taltz," “FDA approves Amjevita, a biosimilar to Humira,” "Cosentyx Medication Guide," "FDA approves new psoriasis drug," "Taltz Medication Guide."

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

PubMed Health: “Certolizumab (Injection),” “Golimumab (Injection).”

Reviewed by Stephanie S. Gardner on July 17, 2019

SOURCES:

Abel, E. "Psoriasis," ACP Medicine, BC Decker, 2005.

American Academy of Dermatology.

Amgen Prescribing Information, Amjevita.

Bruce E. Strober, MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to Amgen, Biogen, Genentech, Fujisawa, NexGenix Pharmaceuticals Holdings Inc. and 3M.

Coxentyx.com. 

FDA: "FDA approves new psoriasis drug Taltz," “FDA approves Amjevita, a biosimilar to Humira,” "Cosentyx Medication Guide," "FDA approves new psoriasis drug," "Taltz Medication Guide."

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

PubMed Health: “Certolizumab (Injection),” “Golimumab (Injection).”

Reviewed by Stephanie S. Gardner on July 17, 2019

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What is certolizumab (Cimzia)?

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