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What is the link between biologics and infections?

ANSWER

Your immune system helps your body fight infections. Since biologics lower those defenses, taking them could make you more likely to get other infections and diseases. Some of these drugs could cause a long-term disease that your body now has under control, like tuberculosis, to flare up again. Your doctor may not prescribe them if you take other medications that curb the immune system. You could get a serious infection because your body can't fight off fungi, bacteria, or viruses the way it usually does

SOURCES:

Abel, E. "Psoriasis," ACP Medicine, BC Decker, 2005.

American Academy of Dermatology.

Amgen Prescribing Information, Amjevita.

Bruce E. Strober, MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to Amgen, Biogen, Genentech, Fujisawa, NexGenix Pharmaceuticals Holdings Inc. and 3M.

Coxentyx.com. 

FDA: "FDA approves new psoriasis drug Taltz," “FDA approves Amjevita, a biosimilar to Humira,” "Cosentyx Medication Guide," "FDA approves new psoriasis drug," "Taltz Medication Guide."

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

PubMed Health: “Certolizumab (Injection),” “Golimumab (Injection).”

Reviewed by Stephanie S. Gardner on July 17, 2019

SOURCES:

Abel, E. "Psoriasis," ACP Medicine, BC Decker, 2005.

American Academy of Dermatology.

Amgen Prescribing Information, Amjevita.

Bruce E. Strober, MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to Amgen, Biogen, Genentech, Fujisawa, NexGenix Pharmaceuticals Holdings Inc. and 3M.

Coxentyx.com. 

FDA: "FDA approves new psoriasis drug Taltz," “FDA approves Amjevita, a biosimilar to Humira,” "Cosentyx Medication Guide," "FDA approves new psoriasis drug," "Taltz Medication Guide."

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

PubMed Health: “Certolizumab (Injection),” “Golimumab (Injection).”

Reviewed by Stephanie S. Gardner on July 17, 2019

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When should I call my doctor about infections if I take a biologic medicine?

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