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Can biologics I take for psoriasis make me more likely to get infections?

ANSWER

Your immune system helps your body fight infections. Since biologics lower those defenses, taking them could make you more likely to get other infections and diseases. Some of these drugs could cause a long-term disease that your body now has under control, like tuberculosis, to flare up again. Your doctor may not prescribe them if you take other medications that curb the immune system.

From: Biologic Medications for Psoriasis WebMD Medical Reference

SOURCES:

Abel, E. "Psoriasis," ACP Medicine, BC Decker, 2005.

American Academy of Dermatology.

Amgen Prescribing Information, Amjevita.

Bruce E. Strober, MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to Amgen, Biogen, Genentech, Fujisawa, NexGenix Pharmaceuticals Holdings Inc. and 3M.

Coxentyx.com. 

FDA: "FDA approves new psoriasis drug Taltz," “FDA approves Amjevita, a biosimilar to Humira,” "Cosentyx Medication Guide," "FDA approves new psoriasis drug," "Taltz Medication Guide."

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

PubMed Health: “Certolizumab (Injection),” “Golimumab (Injection).”

Reviewed by Debra Jaliman on November 7, 2018

SOURCES:

Abel, E. "Psoriasis," ACP Medicine, BC Decker, 2005.

American Academy of Dermatology.

Amgen Prescribing Information, Amjevita.

Bruce E. Strober, MD, PhD, associate professor, vice chairman, director of clinical trials, department of dermatology, University of Connecticut; consultant to Amgen, Biogen, Genentech, Fujisawa, NexGenix Pharmaceuticals Holdings Inc. and 3M.

Coxentyx.com. 

FDA: "FDA approves new psoriasis drug Taltz," “FDA approves Amjevita, a biosimilar to Humira,” "Cosentyx Medication Guide," "FDA approves new psoriasis drug," "Taltz Medication Guide."

Jeffrey M. Weinberg, MD, Mount Sinai St. Luke's, New York; associate clinical professor of dermatology, Columbia University College of Physicians and Surgeons; consultant to Amgen and Genentech.

National Institute of Arthritis and Musculoskeletal and Skin Diseases.

National Psoriasis Foundation.

PubMed Health: “Certolizumab (Injection),” “Golimumab (Injection).”

Reviewed by Debra Jaliman on November 7, 2018

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