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What is the link between psoriasis and inflammatory bowel disease (IBD)?

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There's a strong link between psoriasis and inflammatory bowel disease, or IBD. IBD includes Crohn's disease and ulcerative colitis (UC).

After looking at the gene patterns of tens of thousands of people with serious autoimmune diseases, scientists are finding that the same problem genes can be responsible for psoriasis, Crohn's, and UC. These conditions trigger inflammation in similar ways, too.

SOURCES:

Psoriasis: Targets and Therapy: "Psoriasis and inflammatory bowel disease: links and risks."

National Psoriasis Foundation: "Comorbidities associated with psoriatic disease," "About psoriatic arthritis."

CDC: "What is inflammatory bowel disease (IBD)?"

Nature Genetics: "Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci."

Archives of Dermatological Research: "Digestive system in psoriasis: an update."

Journal of the American Academy of Dermatology: "Inflammatory bowel disease among patients with psoriasis treated with ixekizumab: A presentation of adjudicated data from an integrated database of 7 randomized controlled and uncontrolled trials," "Diet and Psoriasis: Part 2. Celiac Disease and Role of a Gluten-Free Diet," "Psoriasis and comorbid diseases: Implications for management."

Autoimmunity Reviews: "Obesity in autoimmune diseases: not a passive bystander."

Celiac Disease Foundation: "What is celiac disease?" "Celiac disease symptoms."

Journal of Dermatological Treatment: "Early intervention in psoriasis and immune-mediated inflammatory diseases: A hypothesis paper," "Interleukin-17 inhibition: role in psoriasis and inflammatory bowel disease."

Mayo Clinic: "Anemia," "Psoriasis."

Arthritis & Rheumatology: "Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis."

British Journal of Dermatology: "Paradoxical ulcerative colitis during adalimumab treatment of psoriasis resolved by switch to ustekinumab."

American College of Gastroenterology: "ACG Expert Tips on Living Well with IBD."

Crohn's & Colitis Foundation: "Extraintestinal IBD Complications," Crohn’s Disease and Ulcerative Colitis: Emotional Factors Q & A.

NHS Choices: "Psoriasis: Living with."

Nursing Research and Practice: "Self-Management in Daily Life with Psoriasis: An Integrative Review of Patient Needs for Structured Education."

Reviewed by Stephanie S. Gardner on January 24, 2019

SOURCES:

Psoriasis: Targets and Therapy: "Psoriasis and inflammatory bowel disease: links and risks."

National Psoriasis Foundation: "Comorbidities associated with psoriatic disease," "About psoriatic arthritis."

CDC: "What is inflammatory bowel disease (IBD)?"

Nature Genetics: "Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci."

Archives of Dermatological Research: "Digestive system in psoriasis: an update."

Journal of the American Academy of Dermatology: "Inflammatory bowel disease among patients with psoriasis treated with ixekizumab: A presentation of adjudicated data from an integrated database of 7 randomized controlled and uncontrolled trials," "Diet and Psoriasis: Part 2. Celiac Disease and Role of a Gluten-Free Diet," "Psoriasis and comorbid diseases: Implications for management."

Autoimmunity Reviews: "Obesity in autoimmune diseases: not a passive bystander."

Celiac Disease Foundation: "What is celiac disease?" "Celiac disease symptoms."

Journal of Dermatological Treatment: "Early intervention in psoriasis and immune-mediated inflammatory diseases: A hypothesis paper," "Interleukin-17 inhibition: role in psoriasis and inflammatory bowel disease."

Mayo Clinic: "Anemia," "Psoriasis."

Arthritis & Rheumatology: "Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis."

British Journal of Dermatology: "Paradoxical ulcerative colitis during adalimumab treatment of psoriasis resolved by switch to ustekinumab."

American College of Gastroenterology: "ACG Expert Tips on Living Well with IBD."

Crohn's & Colitis Foundation: "Extraintestinal IBD Complications," Crohn’s Disease and Ulcerative Colitis: Emotional Factors Q & A.

NHS Choices: "Psoriasis: Living with."

Nursing Research and Practice: "Self-Management in Daily Life with Psoriasis: An Integrative Review of Patient Needs for Structured Education."

Reviewed by Stephanie S. Gardner on January 24, 2019

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What is the link between psoriasis and celiac disease?

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