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What is hereditary angioedema?

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Hereditary angioedema (HAE) is a rare genetic condition that causes swelling under the skin. A certain protein in your body is not in balance. This causes tiny blood vessels to push fluid into nearby areas. That leads to sudden swelling. Although you’ll always have the disease, treatment helps you manage it.

Symptoms usually show up in childhood and get worse during the teen years. Many people don't know HAE is causing their swelling until they're adults. Where you have it, how often the bouts happen, and how strong they are is different for everyone. The attacks can come and go as well as move to different spots during the same bout.

SOURCES:

HAEA: “What is HAE?” "Treating HAE."

AAAAI: “Understanding Hereditary Angioedema.”

Chnniah, N. Australia and New Zealand Journal of Obstetrics and Gynaecology, February 2009.

National Center for Advance Translational Sciences: “Hereditary angioedema.”

National Library of Medicine, Genetics Home Reference: "What is hereditary angioedema?"

NORD: “Angioedema, Hereditary.”

HAECanada: “Frequently Asked Questions.”

Reviewed by Neha Pathak on March 16, 2021

SOURCES:

HAEA: “What is HAE?” "Treating HAE."

AAAAI: “Understanding Hereditary Angioedema.”

Chnniah, N. Australia and New Zealand Journal of Obstetrics and Gynaecology, February 2009.

National Center for Advance Translational Sciences: “Hereditary angioedema.”

National Library of Medicine, Genetics Home Reference: "What is hereditary angioedema?"

NORD: “Angioedema, Hereditary.”

HAECanada: “Frequently Asked Questions.”

Reviewed by Neha Pathak on March 16, 2021

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What causes hereditary angioedema?

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