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How can belsomra (suvorexant) treat insomnia?

ANSWER

Belsomra is the first orexin receptor antagonist approved for treatment of insomnia. Orexins are chemicals that are involved in regulating the sleep-wake cycle and play a role in keeping people awake. Belsomra changes how orexin acts in the brain.

SOURCES: 

U.S. Department of Health and Human Services. 

National Heart, Lung and Blood Institute. 

American Academy of Family Physicians. 

WebMD Medical Reference: "Insomnia" and "Sleep Disorders: Insomnia." 

WebMD Health News: "Oral Spray Sleep Drug Zolpimist Approved." 

FDA: "Silenor Medication Guide."

News release, FDA.

Reviewed by Carol DerSarkissian on July 21, 2017

SOURCES: 

U.S. Department of Health and Human Services. 

National Heart, Lung and Blood Institute. 

American Academy of Family Physicians. 

WebMD Medical Reference: "Insomnia" and "Sleep Disorders: Insomnia." 

WebMD Health News: "Oral Spray Sleep Drug Zolpimist Approved." 

FDA: "Silenor Medication Guide."

News release, FDA.

Reviewed by Carol DerSarkissian on July 21, 2017

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How can doxepin (Silenor) treat insomnia?

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