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How is zolpidem (Ambien, Edluar, Intermezzo) used to treat insomnia?

ANSWER

These drugs work well at helping you get to sleep, but some people tend to wake up in the middle of the night. Zolpidem is now available in an extended release version, which may help you go to sleep and stay asleep longer. But there are warnings that you should not drive or do anything that requires alertness the day after you take this medication, because it stays in your body for a long time.

SOURCES: 

Clinicaltrials.gov. 

Takeda Pharmaceuticals. 

Neurocrine Biosciences. 

Provogil.com. 

The National Sleep Foundation. 

Donna Arand, clinical director, Kettering Sleep Disorders Center, Kettering, Ohio. 

Thomas Roth, MD, director, Sleep Disorders and Research Center, Henry Ford Health System, Detroit. 

FDA Health Advisory, March 14, 2007. 

WebMD Medical News: "Oral Spray Drug Zolpimist Approved." 

FDA: "Silenor Medication Guide." 

News release, FDA.

Reviewed by Sabrina Felson on January 22, 2020

SOURCES: 

Clinicaltrials.gov. 

Takeda Pharmaceuticals. 

Neurocrine Biosciences. 

Provogil.com. 

The National Sleep Foundation. 

Donna Arand, clinical director, Kettering Sleep Disorders Center, Kettering, Ohio. 

Thomas Roth, MD, director, Sleep Disorders and Research Center, Henry Ford Health System, Detroit. 

FDA Health Advisory, March 14, 2007. 

WebMD Medical News: "Oral Spray Drug Zolpimist Approved." 

FDA: "Silenor Medication Guide." 

News release, FDA.

Reviewed by Sabrina Felson on January 22, 2020

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