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How is zolpidem (Ambien, Edluar, Intermezzo) used to treat insomnia?

ANSWER

These drugs work well at helping you get to sleep, but some people tend to wake up in the middle of the night. Zolpidem is now available in an extended release version, Ambien CR. This may help you go to sleep and stay asleep longer. There is, however, a warning from the FDA that you should not drive or perform any activities that require you to be alert the day after taking Ambien CR because it stays in the body a long time. You should not take zolpidem unless you are able to get a full night's sleep -- at least seven to eight hours. The FDA has approved a prescription oral spray called Zolpimist, which contains zolpidem, for the short-term treatment of insomnia brought on by difficulty falling asleep.

From: Drugs to Treat Insomnia WebMD Medical Reference

SOURCES: 

Clinicaltrials.gov. 

Takeda Pharmaceuticals. 

Neurocrine Biosciences. 

Provogil.com. 

The National Sleep Foundation. 

Donna Arand, clinical director, Kettering Sleep Disorders Center, Kettering, Ohio. 

Thomas Roth, MD, director, Sleep Disorders and Research Center, Henry Ford Health System, Detroit. 

FDA Health Advisory, March 14, 2007. 

WebMD Medical News: "Oral Spray Drug Zolpimist Approved." 

FDA: "Silenor Medication Guide." 

News release, FDA.

Reviewed by Melinda Ratini on August 14, 2017

WAS THIS ANSWER HELPFUL

SOURCES: 

Clinicaltrials.gov. 

Takeda Pharmaceuticals. 

Neurocrine Biosciences. 

Provogil.com. 

The National Sleep Foundation. 

Donna Arand, clinical director, Kettering Sleep Disorders Center, Kettering, Ohio. 

Thomas Roth, MD, director, Sleep Disorders and Research Center, Henry Ford Health System, Detroit. 

FDA Health Advisory, March 14, 2007. 

WebMD Medical News: "Oral Spray Drug Zolpimist Approved." 

FDA: "Silenor Medication Guide." 

News release, FDA.

Reviewed by Melinda Ratini on August 14, 2017

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