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What are common medical causes of periodic limb movement disorder?

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  • Diabetes mellitus
  • Iron deficiency or anemia
  • Spinal cord tumor or injury
  • Sleep apnea
  • Narcolepsy
  • Uremia from poor kidney function
  • Medication such as neuroleptics and other antidopaminergic agents or tricyclic antidepressants
  • Withdrawal from sedative medications such as barbiturates or benzodiazepines

Many causes of secondary PLMD can also cause restless legs syndrome.

Author: Wayne E Anderson, DO, Assistant Professor of Internal Medicine/Neurology, Western University of Health Sciences; Consulting Staff, Department of Neurology, Pain Management, California Pacific Medical Center. Editors: Selim R Benbadis, MD, Director of Comprehensive Program, Professor, Departments of Neurology and Neurosurgery, University of South Florida, Tampa General Hospital; Mary L Windle, Pharm D, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Pharmacy Editor, eMedicine.com, Inc; Stephen Berman, MD, PhD, Professor, Department of Internal Medicine, Section of Neurology, Dartmouth Medical School; Chief, White River Junction VA Neurology Service, White River Junction VA Hospital.  


Epilepsy

Periodic Limb Movement Disorder from eMedicineHealth

Reviewed by Carol DerSarkissian on May 15, 2018

Author: Wayne E Anderson, DO, Assistant Professor of Internal Medicine/Neurology, Western University of Health Sciences; Consulting Staff, Department of Neurology, Pain Management, California Pacific Medical Center. Editors: Selim R Benbadis, MD, Director of Comprehensive Program, Professor, Departments of Neurology and Neurosurgery, University of South Florida, Tampa General Hospital; Mary L Windle, Pharm D, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Pharmacy Editor, eMedicine.com, Inc; Stephen Berman, MD, PhD, Professor, Department of Internal Medicine, Section of Neurology, Dartmouth Medical School; Chief, White River Junction VA Neurology Service, White River Junction VA Hospital.  


Epilepsy

Periodic Limb Movement Disorder from eMedicineHealth

Reviewed by Carol DerSarkissian on May 15, 2018

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What are symptoms of periodic limb movement disorder?

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