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What medications are used to treat narcolepsy relative to excessive sleepiness?

ANSWER

Your doctor may prescribe these medications:

  • Stimulants such as armodafinil, modafinil, methylphenidate, or dextroamphetamine are most commonly used to help people stay awake.
  • Antidepressants such as tricyclics or serotonin reuptake inhibitors can help with cataplexy, hallucinations, and sleep paralysis.
  • Sodium oxybate (Xyrem), a central nervous system depressant, helps control cataplexy, when a person suddenly feels weak or collapses.
  • Solriamfetrol (Sunosi) a dual-acting dopamine and norepinephromere uptake inhibitor helps patients stay awake longer. ,

SOURCES: 

News release, FDA.

National Institute of Neurological Disorders and Stroke: “NINDS Hypersomnia Information Page.”

Medscape: “Management of Excessive Daytime Sleepiness Reviewed.”

eMedicine: “Primary Hypersomnia.” 

eMedicine: “Obstructive Sleep Apnea.” 

eMedicine: “Disorders that Disrupt Sleep (Parasomnias).”

National Sleep Foundation: “Fatigue and Excessive Sleepiness.”

National Sleep Foundation: “Depression and Sleep.”

Narcolepsy Network: “FAQ.”

RLS Foundation: “What Is RLS?” 

RLS Foundation: “FAQ.”

Reviewed by Carol DerSarkissian on May 22, 2019

SOURCES: 

News release, FDA.

National Institute of Neurological Disorders and Stroke: “NINDS Hypersomnia Information Page.”

Medscape: “Management of Excessive Daytime Sleepiness Reviewed.”

eMedicine: “Primary Hypersomnia.” 

eMedicine: “Obstructive Sleep Apnea.” 

eMedicine: “Disorders that Disrupt Sleep (Parasomnias).”

National Sleep Foundation: “Fatigue and Excessive Sleepiness.”

National Sleep Foundation: “Depression and Sleep.”

Narcolepsy Network: “FAQ.”

RLS Foundation: “What Is RLS?” 

RLS Foundation: “FAQ.”

Reviewed by Carol DerSarkissian on May 22, 2019

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How is depression relative to excessive sleepiness treated?

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