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What are the second-line treatments for interstitial cystitis?

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If lifestyle changes aren’t enough, then try the next line of treatments:

  • Physical therapy to help relax your pelvic muscles.
  • Amitriptyline. This drug controls bladder spasms. It’s the most widely used oral medication for interstitial cystitis.
  • Pentosan (Elmiron). It’s not clear how this drug works, but it might help rebuild the bladder tissue lining. It can take a few months to relieve symptoms.
  • Hydroxyzine. This drug is an antihistamine and can be helpful if you have to urinate a lot at night.

From: Interstitial Cystitis WebMD Medical Reference

SOURCES:

National Institute of Diabetes and Digestive and Kidney Diseases: “Interstitial Cystitis/Painful Bladder Syndrome.”

Urology Care Foundation: “Symptoms,” Treatment,” “After Initial Treatment.”

Harvard Medical School: “Diagnosing and Treating Interstitial Cystitis.”

Interstitial Cystitis Association: “4 to 12 Million May Have IC.”

Office on Women’s Health, U.S. Department of Health and Human Services: “Interstitial cystitis/bladder pain syndrome fact sheet.”

UpToDate: “Management of interstitial cystitis/bladder pain syndrome.”

Reviewed by Michael W. Smith on October 23, 2017

SOURCES:

National Institute of Diabetes and Digestive and Kidney Diseases: “Interstitial Cystitis/Painful Bladder Syndrome.”

Urology Care Foundation: “Symptoms,” Treatment,” “After Initial Treatment.”

Harvard Medical School: “Diagnosing and Treating Interstitial Cystitis.”

Interstitial Cystitis Association: “4 to 12 Million May Have IC.”

Office on Women’s Health, U.S. Department of Health and Human Services: “Interstitial cystitis/bladder pain syndrome fact sheet.”

UpToDate: “Management of interstitial cystitis/bladder pain syndrome.”

Reviewed by Michael W. Smith on October 23, 2017

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What are third-line treatments for interstitial cystitis?

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