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Does ethylenediaminetetraacetic acid (EDTA) work?

ANSWER

EDTA is a molecule called a chelating agent, which grab and stick to other molecules. Supplement makers claim that over-the-counter forms of EDTA can be taken by mouth to "detox" the body and make your gastrointestinal tract healthier. There is no scientific evidence to support this.

Preliminary studies show that intravenous EDTA therapy under physician supervision may help patients who have had a heart attack, particularly if they have diabetes. However, more study is needed to prove this.

SOURCES:

News releases, Natural Standard.

News release, FDA.

FDA web site: "Warning Letter NYK-2011-02," "Food Additives List."

Science News , Sept. 13, 1997.

Rakel, R.E., editor, 8th edition, Saunders Elsevier, 2011. Textbook of Family Medicine,

Natural Standard: "Chelation."

Curr Cardiol Rep. : "EDTA Chelation Therapy to Reduce Cardiovascular Events in Persons with Diabetes." 

JAMA : "Effect of disodium EDTA chelation regimen on cardiovascular events in patients with previous myocardial infarction: The TACT Randomized Trial."

Circulation : "Clinical benefit of EDTA chelation therapy in patients with diabetes in the trial to assess chelation therapy (TACT)."

Reviewed by Melinda Ratini on March 26, 2020

SOURCES:

News releases, Natural Standard.

News release, FDA.

FDA web site: "Warning Letter NYK-2011-02," "Food Additives List."

Science News , Sept. 13, 1997.

Rakel, R.E., editor, 8th edition, Saunders Elsevier, 2011. Textbook of Family Medicine,

Natural Standard: "Chelation."

Curr Cardiol Rep. : "EDTA Chelation Therapy to Reduce Cardiovascular Events in Persons with Diabetes." 

JAMA : "Effect of disodium EDTA chelation regimen on cardiovascular events in patients with previous myocardial infarction: The TACT Randomized Trial."

Circulation : "Clinical benefit of EDTA chelation therapy in patients with diabetes in the trial to assess chelation therapy (TACT)."

Reviewed by Melinda Ratini on March 26, 2020

NEXT QUESTION:

Which foods contain ethylenediaminetetraacetic acid (EDTA)?

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