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What are side effects of nattokinase?

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In food, nattokinase is safe. More studies are needed to see if nattokinase taken as a supplement is safe for repeated or long-term use. Tell your doctor about any supplements you're taking, even if they're natural. That way, your doctor can check on any potential side effects or interactions with medications.

SOURCES:

Murakami, K. Food & Function, 2012.

Natural Medicines Comprehensive Database web site: "Nattokinase."

Nagata C. Dietary soy and natto intake and cardiovascular disease mortality in Japanese adults: the Takayama study. 2017

Kim JY, Gum SN, Paik JK, Lim HH, Kim K-C, Ogasawara K, Inoue K, Park S, Jang Y, Lee JH. Effects of nattokinase on blood pressure: a randomized, controlled trial. 2008

Hsia CH, Shen MC, Lin JS, Wen YK, Hwang KL, Chamm TM, Yang NC. Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects. 2009

 

Reviewed by Melinda Ratini on September 24, 2019

SOURCES:

Murakami, K. Food & Function, 2012.

Natural Medicines Comprehensive Database web site: "Nattokinase."

Nagata C. Dietary soy and natto intake and cardiovascular disease mortality in Japanese adults: the Takayama study. 2017

Kim JY, Gum SN, Paik JK, Lim HH, Kim K-C, Ogasawara K, Inoue K, Park S, Jang Y, Lee JH. Effects of nattokinase on blood pressure: a randomized, controlled trial. 2008

Hsia CH, Shen MC, Lin JS, Wen YK, Hwang KL, Chamm TM, Yang NC. Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects. 2009

 

Reviewed by Melinda Ratini on September 24, 2019

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What are risks of taking nattokinase?

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