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What are the risks of taking L-citrulline?

ANSWER

There are no reported side effects of L-citrulline, but it may affect the way certain drugs work in your body. Don't take it if you take:

You should also be careful when taking L-citrulline if you take any type of blood pressure medicine. Do not use L-citrulline if you are pregnant or breastfeeding. Always tell your doctor about any supplements you take.

  • Nitrates for heart disease
  • Erectile dysfunction drugs such as Cialis, Levitra, or Viagra

SOURCES:

News releases, National Standard Database: "L-Citrulline May Lower Blood Pressure," "Watermelon and Viagra."

Venes, D., editor, , 19th edition. F.A. Davis Company, 2001. Taber's Cyclopedic Medical Dictionary

Cormio, L. , January 2011. Urology

Smith, H. , July 2006. The Journal of Thoracic and Cardiovascular Surgery

Sureda, A. , 2013. Medicine and Sport Science

National Medicines Comprehensive Medicines web site. "L-Citrulline Monograph."

DiPetrio, N. , Nov. 8, 2012. Atherosclerosis

Osowska, S. , 2006. American Journal of Physiology, Endocrinology, and Metabolism

Curis, E. , 2005. Amino Acids

Carpenter, T.O.  , 1985. New England Journal of Medicine

Jesse, S. June 2009. CNS Neuroscience and Therapeutics,

Tremblay, G.C. , 1975. New England Journal of Medicine

Mandel H. , 2005. Journal of Inherited Metabolic Disease

Diego M. C., Zhao-Jun Liu, Omaida C. V. 2012 Oxygen: Implications of Wound Healing,

Reviewed by Melinda Ratini on September 24, 2019

SOURCES:

News releases, National Standard Database: "L-Citrulline May Lower Blood Pressure," "Watermelon and Viagra."

Venes, D., editor, , 19th edition. F.A. Davis Company, 2001. Taber's Cyclopedic Medical Dictionary

Cormio, L. , January 2011. Urology

Smith, H. , July 2006. The Journal of Thoracic and Cardiovascular Surgery

Sureda, A. , 2013. Medicine and Sport Science

National Medicines Comprehensive Medicines web site. "L-Citrulline Monograph."

DiPetrio, N. , Nov. 8, 2012. Atherosclerosis

Osowska, S. , 2006. American Journal of Physiology, Endocrinology, and Metabolism

Curis, E. , 2005. Amino Acids

Carpenter, T.O.  , 1985. New England Journal of Medicine

Jesse, S. June 2009. CNS Neuroscience and Therapeutics,

Tremblay, G.C. , 1975. New England Journal of Medicine

Mandel H. , 2005. Journal of Inherited Metabolic Disease

Diego M. C., Zhao-Jun Liu, Omaida C. V. 2012 Oxygen: Implications of Wound Healing,

Reviewed by Melinda Ratini on September 24, 2019

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