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Why do people take L-citrulline?

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L-citrulline boosts nitric oxide production in the body. Nitric oxide helps your arteries relax and work better, which improves blood flow throughout your body. This may be helpful for treating or preventing some diseases. There is some evidence to suggest the supplement could possibly help lower blood pressure in people with prehypertension. This is an early warning sign for high blood pressure. It means you have a slightly raised blood pressure reading of 120/80 to 139/89. Prehypertension raises your risk for high blood pressure and heart disease. L-citrulline supplements may ease symptoms of mild-to-moderate erectile dysfunction (ED). Scientists say L-citrulline does not work as well as ED drugs such as Viagra. However, it appears to be a safe option. Animal studies suggest L-citrulline might also help people with blood vessel problems such as slow wound healing due to diabetes. Other animal research says L-citrulline might improve muscle protein levels and prevent malnourishment in the elderly.

From: L-citrulline WebMD Medical Reference

SOURCES:

News releases, National Standard Database: "L-Citrulline May Lower Blood Pressure," "Watermelon and Viagra."

Venes, D., editor, , 19th edition. F.A. Davis Company, 2001. Taber's Cyclopedic Medical Dictionary

Cormio, L. , January 2011. Urology

Smith, H. , July 2006. The Journal of Thoracic and Cardiovascular Surgery

Sureda, A. , 2013. Medicine and Sport Science

National Medicines Comprehensive Medicines web site. "L-Citrulline Monograph."

DiPetrio, N. , Nov. 8, 2012. Atherosclerosis

Osowska, S. , 2006. American Journal of Physiology, Endocrinology, and Metabolism

Curis, E. , 2005. Amino Acids

Carpenter, T.O.  , 1985. New England Journal of Medicine

Jesse, S. June 2009. CNS Neuroscience and Therapeutics,

Tremblay, G.C. , 1975. New England Journal of Medicine

Mandel H. , 2005. Journal of Inherited Metabolic Disease

Diego M. C., Zhao-Jun Liu, Omaida C. V. 2012 Oxygen: Implications of Wound Healing,

Reviewed by Melinda Ratini on September 29, 2019

SOURCES:

News releases, National Standard Database: "L-Citrulline May Lower Blood Pressure," "Watermelon and Viagra."

Venes, D., editor, , 19th edition. F.A. Davis Company, 2001. Taber's Cyclopedic Medical Dictionary

Cormio, L. , January 2011. Urology

Smith, H. , July 2006. The Journal of Thoracic and Cardiovascular Surgery

Sureda, A. , 2013. Medicine and Sport Science

National Medicines Comprehensive Medicines web site. "L-Citrulline Monograph."

DiPetrio, N. , Nov. 8, 2012. Atherosclerosis

Osowska, S. , 2006. American Journal of Physiology, Endocrinology, and Metabolism

Curis, E. , 2005. Amino Acids

Carpenter, T.O.  , 1985. New England Journal of Medicine

Jesse, S. June 2009. CNS Neuroscience and Therapeutics,

Tremblay, G.C. , 1975. New England Journal of Medicine

Mandel H. , 2005. Journal of Inherited Metabolic Disease

Diego M. C., Zhao-Jun Liu, Omaida C. V. 2012 Oxygen: Implications of Wound Healing,

Reviewed by Melinda Ratini on September 29, 2019

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What are the benefits of taking L-citrulline?

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THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

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