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    Other Names:

    2-aminopropionic Acid, Acide Alpha-aminopropionique, Acide Aminé Alanine, Acide Aminé Non Essentiel, Ala, Alanine Amino Acid, Alfa-alanina, Alpha-aminopropionic Acid, D-alanine, D-alpha-alanine, DL-alanine, L-alanine, L-alpha-alanine, L-alpha-am...
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    ALPHA-ALANINE Overview
    ALPHA-ALANINE Side Effects
    ALPHA-ALANINE Interactions
    ALPHA-ALANINE Overview Information

    Alpha-alanine is a non-essential amino acid. Non-essential amino acids can be made by the body, so they don’t have to be provided by food. Amino acids are the building blocks of proteins.

    You may see the terms “L-alpha-alanine” and “D-alpha-alanine.“ The “L” refers to the “left-handed” chemical form of the alpha-alanine molecule. The “D” refers to the “right-handed” chemical form of the molecule. The L and D forms are mirror-images of each other.

    Alpha-alanine is used for low blood sugar (hypoglycemia), diarrhea-related dehydration, liver disease, enlarged prostate (benign prostatic hypertrophy, BPH), fatigue, stress, and certain inherited disorders including glycogen storage disease and urea cycle disorders.

    How does it work?

    Alpha-alanine is an amino acid. It can affect blood sugar levels.

    ALPHA-ALANINE Uses & Effectiveness What is this?

    Possibly Effective for:

    Insufficient Evidence for:

    • Diarrhea-related dehydration. Studies to date have produced mixed results about the effectiveness of L-alpha-alanine in treating dehydration due to diarrhea.
    • An inherited disorder called glycogen storage disease. There is some evidence that L-alpha-alanine can improve some, but not all, symptoms of the disease.
    • Schizophrenia. Early research suggests D-alpha-alanine might help regular drugs work better for improving symptoms in people with schizophrenia.
    • Liver disease.
    • Enlarged prostate (benign prostatic hypertrophy, BPH).
    • Fatigue.
    • Stress.
    • Urea cycle disorders.
    • Other conditions.
    More evidence is needed to rate the effectiveness of alpha-alanine for these uses.

    ALPHA-ALANINE Side Effects & Safety

    Alpha-alanine seems to be safe when used appropriately for a short time. Side effects have not been reported in studies of alpha-alanine.

    Special Precautions & Warnings:

    Pregnancy and breast-feeding: Not enough is known about the use of alpha-alanine during pregnancy and breast-feeding. Stay on the safe side and avoid use.

    Diabetes: L-alpha-alanine can increase blood sugar levels in people with diabetes. This can be helpful if blood sugar levels are too low, but it can be harmful if blood sugar levels are normal or too high. Monitor your blood sugar carefully if you have diabetes and use alpha-alanine.

    ALPHA-ALANINE Interactions What is this?

    We currently have no information for ALPHA-ALANINE Interactions


    The following doses have been studied in scientific research:


    • For treating low blood sugar in people with type 1 diabetes due to too much insulin: 20-40 grams of L-alpha-alanine.
    • For preventing low blood sugar at night in people with type 1 diabetes: 40 grams of L-alpha-alanine at bedtime along with 10 grams of glucose (sugar).

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    Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

    This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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