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    Other Names:

    1,3-Dimethylamylamine, 1,3-Dimethyl-5-Amine, 1,3-Dimethylamylamine HCL, 1,3 Dimethylpentylamine, 1,3-dimethylpentylamine, 2-amino-4-methylhexane, 2-Hexanamine,4-Methyl-(9Cl), 4-methyl-2-hexanamine, 4-methyl-2-hexyl-amine, 4-methylhexan-2-amine,...
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    DIMETHYLAMYLAMINE Overview Information

    Dimethylamylamine is a drug made synthetically in a laboratory. It was originally used as a nasal decongestant. Today, dimethylamylamine is sold as a dietary supplement used for attention deficit-hyperactive disorder (ADHD), weight loss, improving athletic performance, and body building.

    Some products claim that dimethylamylamine naturally comes from rose geranium oil. Supplements that contain this ingredient sometimes list rose geranium, geranium oil, or geranium stems on the label. However, laboratory analysis shows that this drug probably does not come from this natural source. It is thought that these manufacturers have artificially added this drug to the supplement rather than obtaining it from a natural source. Dimethylamylamine is considered a drug in Canada and is not permitted in dietary supplements or natural health products.

    Many athletes take dimethylamylamine to improve performance. However, dimethylamylamine was added to the World Anti-Doping Agency's prohibited substances list in 2010. Therefore, competitive athletes should avoid taking it.

    Due to safety concerns, dimethylamylamine has been removed from military stores in the US. It has also been banned in New Zealand. The US Food and Drug Administration (FDA) considers supplements containing dimethylamylamine to be illegal. Its use has been linked to several reports of serious, life-threatening side effects.

    How does it work?

    Dimethylamylamine is thought to have stimulant effects similar to decongestants such as pseudoephedrine, ephedrine, and others. Some promoters say that it is a safer alternative to ephedrine. However, there is no scientific information to back up this claim.

    DIMETHYLAMYLAMINE Uses & Effectiveness What is this?

    Insufficient Evidence for:

    • Weight loss. Early research shows that taking dimethylamylamine does not seem to help with weight loss.
    • Attention deficit-hyperactive disorder (ADHD).
    • Athletic performance.
    • Body building.
    • Other conditions.
    More evidence is needed to rate dimethylamylamine for these uses.

    DIMETHYLAMYLAMINE Side Effects & Safety

    Dimethylamylamine is LIKELY UNSAFE when taken by mouth. Since it is thought to work like a stimulant, there is concern that it might increase the chance of serious side effects such as rapid heartbeat, increased blood pressure, and increased risk of heart attack or stroke.

    There have been several reports of dangerous side effects including stroke, a condition called lactic acidosis, heart attack, liver injury, and death in people who have taken dimethylamylamine.

    Special Precautions & Warnings:

    Pregnancy and breast-feeding: Not enough is known about the use of dimethylamylamine during pregnancy and breast-feeding. Stay on the safe side and avoid use.

    High blood pressure: Dimethylamylamine might have stimulant effects and can increase blood pressure. If you have high blood pressure, avoid taking dimethylamylamine.

    Glaucoma: Dimethylamylamine might have stimulant effects and cause blood vessels to constrict. This could worsen some types of glaucoma. If you have glaucoma, avoid taking dimethylamylamine.

    Irregular heartbeat (heart arrhythmia): Dimethylamylamine might have stimulant effects and can cause a rapid heartbeat. This could worsen heart arrhythmias.

    Surgery: Dimethylamylamine might have stimulant effects, so it might interfere with surgery by increasing heart rate and blood pressure. Stop taking dimethylamylamine at least 2 weeks before a scheduled surgery.

    DIMETHYLAMYLAMINE Interactions What is this?

    We currently have no information for DIMETHYLAMYLAMINE Interactions


    The appropriate dose of dimethylamylamine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for dimethylamylamine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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    Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

    This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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