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    Other Names:

    1-Amino-2-phenylethane, 2-Phenethylamine, 2-Phenylethylamine, Benzeneethanamine, Beta-phenethylamine, Beta-phenylethylamine, PEA, Phenethylamine HCl, Phenethylamine Hydrochloride, Phenylethylamine.

    PHENETHYLAMINE Interactions
    PHENETHYLAMINE Overview Information

    Phenethylamine is a chemical that is found naturally in the body. It can also be made in the laboratory.

    Phenethylamine is taken by mouth for improving athletic performance, depression, weight loss, and to improve mood and attention.

    How does it work?

    Phenethylamine stimulates the body to make certain chemicals that play a role in depression and other psychiatric conditions. People who don’t make enough phenethylamine naturally may be helped by taking phenethylamine as a supplement. However, too much phenethylamine might cause side effects similar to the drug amphetamine.

    PHENETHYLAMINE Uses & Effectiveness What is this?

    Insufficient Evidence for:

    • Depression. Early research shows that taking 10-60 mg of phenethylamine by mouth per day along with 5 mg of the antidepressant selegiline (Anipryl, Eldepryl) twice per day for 4 weeks relieves depression in 60% of people. Of the people who respond to initial treatment with phenethylamine plus selegiline, 86% show continued depression relief when treated for up to 50 weeks.
    • Attention.
    • Mood.
    • Weight loss.
    • Other conditions.
    More evidence is needed to rate phenethylamine for these uses.

    PHENETHYLAMINE Side Effects & Safety

    Phenethylamine is POSSIBLY UNSAFE for most people when taken by mouth appropriately. Phenethylamine works similar to the drug amphetamine, and may cause similar side effects. Also, it might cause rapid heart rate, anxiety, or agitation.

    Special Precautions & Warnings:

    Pregnancy and breast-feeding: Not enough is known about the safety of using phenethylamine during pregnancy and breast-feeding. Stay on the safe side and avoid use.

    Bipolar disorder: Use of phenethylamine might cause people with bipolar disorder to convert from depression to mania.

    Schizophrenia: Use of phenethylamine might worsen symptoms of schizophrenia, including hallucinations or delusions.

    Surgery: Phenethylamine might affect the central nervous system. This could interfere with surgery. Stop taking phenethylamine at least 2 weeks before a scheduled surgery.

    PHENETHYLAMINE Interactions What is this?

    We currently have no information for PHENETHYLAMINE Interactions


    The appropriate dose of phenethylamine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for phenethylamine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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    This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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