MARAL ROOT: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Maral root is part of a plant. The roots are used to make medicine.

People use maral root for athletic performance, depression, sexual problems that prevent satisfaction during sexual activity, and many other conditions, but there is no good scientific evidence to support these uses.

How does it work ?

There isn't enough reliable information available to know how maral root might work.

Uses & Effectiveness ?

Insufficient Evidence for

Athletic performance.
Depression.
Conditions in a man that prevent him from getting a woman pregnant within a year of trying to conceive (male infertility).
Parasites.
Sexual problems that prevent satisfaction during sexual activity.
Other conditions.

More evidence is needed to rate the effectiveness of maral root for these uses.

Side Effects

When taken by mouth: There isn't enough reliable information to know if maral root is safe or what the side effects might be.

Special Precautions and Warnings

When taken by mouth: There isn't enough reliable information to know if maral root is safe or what the side effects might be. Pregnancy and breast-feeding: There isn't enough reliable information to know if maral root is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Allergy to ragweed and related plants: Maral root may cause an allergic reaction in people who are allergic to the Asteraceae/Compositae plant family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking maral root.

Bleeding disorders: Maral root might slow blood clotting. In theory, maral root might increase the risk of bruising and bleeding in people with bleeding disorders.

Surgery: Maral root might slow blood clotting. There is concern that it might increase the risk of bleeding during and after surgery. Stop using maral root at least 2 weeks before a scheduled surgery.

Interactions ?

Moderate Interaction

Be cautious with this combination

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with MARAL ROOT
Maral root might slow blood clotting. Taking maral root along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others.

Dosing

The appropriate dose of maral root depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for maral root. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

Azizov AP, Seifulla RD, Chubarova AV. [Effects of leuzea tincture and leveton on humoral immunity of athletes]. Eksp Klin Farmakol 1997;60(6):47-8. View abstract.

Azizov, A. P. [Effects of eleutherococcus, elton, leuzea, and leveton on the blood coagulation system during training in athletes]. Eksp Klin Farmakol 1997;60(5):58-60. View abstract.

Azizov, A. P. and Seifulla, R. D. [The effect of elton, leveton, fitoton and adapton on the work capacity of experimental animals]. Eksp Klin Farmakol 1998;61(3):61-63. View abstract.

Bespalov, V. G., Aleksandrov, V. A., Iaremenko, K. V., Davydov, V. V., Lazareva, N. L., Limarenko, A. I., Slepian, L. I., Petrov, A. S., and Troian, D. N. [The inhibiting effect of phytoadaptogenic preparations from bioginseng, Eleutherococcus senticosus and Rhaponticum carthamoides on the development of nervous system tumors in rats induced by N-nitrosoethylurea]. Vopr Onkol 1992;38(9):1073-1080. View abstract.

Budesinsky M, Vokac K, Harmatha J, Cvacka J. Additional minor ecdysteroid components of Leuzea carthamoides. Steroids 2008;73(5):502-14. View abstract.

Chobot V, Buchta V, Jahodarova H, et al. Antifungal activity of a thiophene polyine from Leuzea carthamoides. Fitoterapia 2003;74(3):288-90. View abstract.

Chobot V, Vytlacilova J, Kubicova L, et al. Phototoxic activity of a thiophene polyacetylene from Leuzea carthamoides. Fitoterapia 2006;77(3):194-8. View abstract.

Gadzhieva RM, Portugalov SN, Paniushkin VV, Kondrat'eva II. [A comparative study of the anabolic action of ecdysten, leveton and Prime Plus, preparations of plant origin]. Eksp Klin Farmakol 1995;58(5):46-8. View abstract.

Gaube F, Wolfl S, Pusch L, et al. Effects of Leuzea carthamoides on human breast adenocarcinoma MCF-7 cells determined by gene expression profiling and functional assays. Planta Med 2008;74(14):1701-8. View abstract.

Geszprych A, Weglarz Z. Composition of essential oil from underground and aboveground organs of Rhaponticum carthamoides (Willd.) Iljin. Herba Polonica 2002;48(4):188-92.

Hajdu Z, Varga E, Hohmann J, et al. A stilbene from the roots of leuzea carthamoides. J Nat Prod 1998;61(10):1298-9. View abstract.

Havlik J, Budesinsky M, Kloucek P, et al. Norsesquiterpene hydrocarbon, chemical composition and antimicrobial activity of Rhaponticum carthamoides root essential oil. Phytochemistry 2009;70(3):414-8. View abstract.

Ibatov AN. [The use of a decoction of the rhizome of Leuzea carthamoides for the treatment of alcoholics with depressive states]. Zh Nevrol Psikhiatr Im S S Korsakova 1995;95(4):78-9. View abstract.

Khalid SA, Varga E, Szendrei K, Duddeck H. Isolation of Lanosta-9(11),24dien-3beta-yl acetate from Leuzea carthamoides. J Nat Prod 1989;52(5):1136-8.

Kholodova IuD, Tugai VA, Zimina VP. [Effect of vitamin D3 and 20-hydroxyecdysone on the content of ATP, creatine phosphate, carnosine and Ca2+ in skeletal muscles]. Ukr Biokhim Zh (1978) 1997;69(3):3-9. View abstract.

Kokoska L, Janovska D. Chemistry and pharmacology of Rhaponticum carthamoides: a review. Phytochemistry 2009;70(7):842-55. View abstract.

Kokoska L, Polesny Z, Rada V, et al. Screening of some Siberian medicinal plants for antimicrobial activity. J Ethnopharmacol 2002;82:51-3. View abstract.

Koleckar V, Brojerova E, Rehakova Z, et al. In vitro antiplatelet activity of flavonoids from Leuzea carthamoides. Drug Chem Toxicol 2008;31(1):27-35. View abstract.

Koleckar V, Opletal L, Brojerova E, et al. Evaluation of natural antioxidants of Leuzea carthamoides as a result of a screening study of 88 plant extracts from the European Asteraceae and Cichoriaceae. J Enzyme Inhib Med Chem 2008;23(2):218-24. View abstract.

Kormosh, N., Laktionov, K., and Antoshechkina, M. Effect of a combination of extract from several plants on cell-mediated and humoral immunity of patients with advanced ovarian cancer. Phytother Res 2006;20(5):424-425. View abstract.

Kuz'menko AI, Morozova RP, Nikolenko IA, Donchenko GV. Antioxidant effect of 20-hydroxyecdysone in a model system. Ukr Biokhim Zh (1999) 1999;71(3):35-8. View abstract.

Logvinov SV, Pugachenko NV, Potapov AV, et al. Ischemia-induced changes in synaptoarchitectonics of brain cortex and their correction with ascovertin and Leuzea extract. Bull Exp Biol Med 2001;132(4):1017-20. View abstract.

Maslov, L. N. and Guzarova, N. V. [Cardioprotective and antiarrhythmic properties of preparations from Leuzea carthamoides, Aralia mandshurica, and Eleutherococcus senticosus]. Eksp Klin Farmakol 2007;70(6):48-54. View abstract.

Miliauskas G, van Beek TA, de Waard P, et al. Identification of radical scavenging compounds in Rhaponticum carthamoides by means of LC-DAD-SPE-NMR. J Nat Prod 2005;68(2):168-72. View abstract.

Mirzaev IuR, Syrov VN, Khrushev SA, Iskanderova SD. [Effect of ecdystene on parameters of the sexual function under experimental and clinical conditions]. Eksp Klin Farmakol 2000;63(4):35-7. View abstract.

Opletal L, Sovova M, Dittrich M, et al. [Phytotherapeutic aspects of diseases of the circulatory system. 6. Leuzea carthamoides (WILLD.) DC: the status of research and possible use of the taxon]. Ceska Slov Farm 1997;46(6):247-55. View abstract.

Osipova SO, Islamova ZhI, Syrov VN, et al. [Ecdysten in the treatment of giardiasis]. Med Parazitol (Mosk) 2002;(1):29-33. View abstract.

Pavlik M, Laudova V, Gruner K, et al. High-performance liquid chromatographic analysis and separation of N-feruloylserotonin isomers. J Chromatogr B Analyt Technol Biomed Life Sci 2002;770(1-2):291-5. View abstract.

Plotnikov MB, Aliev OI, Vasil'ev AS, et al. [Effect of Rhaponticum carthamoides extract on hemorheological properties of blood in rats with arterial hypertension]. Eksp Klin Farmakol 2001;64(6):45-7. View abstract.

Plotnikov MB, Aliev OI, Vasil'ev AS, et al. Effect of Rhaponticum carthamoides extract on structural and metabolic parameters of erythrocytes in rats with cerebral ischemia. Bull Exp Biol Med 2008;146(1):45-8. View abstract.

Plotnikov MB, Logvinov SV, Pugachenko NV, et al. [Cerebroprotector activity of Rhaponticum carthamoides extract in rats with brain ischemia]. Eksp Klin Farmakol 2005;68(4):19-23. View abstract.

Sharaf M, Skiba A, Weglarz Z, El-Ansari MA. Two flavonol 5-O-glycosides from the roots of Leuzea carthamoides. Fitoterapia 2001;72(8):940-2. View abstract.

Slama K, Koudela K, Tenora J, Mathova A. Insect hormones in vertebrates: anabolic effects of 20-hydroxyecdysone in Japanese quail. Experientia 1996;52(7):702-6. View abstract.

Sovova H, Opletal L, Sajfrtova M, Bartlova M. Supercritical fluid extraction of cynaropicrin and 20-hydroxyecdysone from Leuzea carthamoides DC. J Sep Sci 2008;31(8):1387-92. View abstract.

Stodulka P, Koleckar V, Jun D, et al. High-performance liquid chromatography analysis of four Leuzea carthamoides flavonoids. J Chromatogr Sci 2008;46(2):162-4. View abstract.

Syrov VN, Kurmukov AG. [Anabolic activity of phytoecdysone-ecdysterone isolated from Rhaponticum carthamoides (Willd.) Iljin]. Farmakol Toksikol 1976;39:690-3. View abstract.

Syrov VN, Nasyrova SS, Khushbaktova ZA. [The results of experimental study of phytoecdysteroids as erythropoiesis stimulators in laboratory animals]. Eksp Klin Farmakol 1997;60(3):41-4. View abstract.

Szendrei K, Reisch J, Erzsebet V. Thiophene acetylenes from Leuzea roots. Phytochemistry 1984;23(4):901-2.

Yamamotova A, Pometlova M, Harmatha J, et al. The selective effect of N-feruloylserotonins isolated from Leuzea carthamoides on nociception and anxiety in rats. J Ethnopharmacol 2007;112(2):368-74. View abstract.