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    Other Names:

    Nicotinamide Ribose, NR, Riboside de nicotinamide.

    NICOTINAMIDE RIBOSIDE Overview Information

    Nicotinamide riboside is a member of the vitamin B3 family. It is found in small amounts in fruits, vegetables, meat, and milk.

    Nicotinamide riboside is taken by mouth for aging and age-related conditions such as Alzheimer disease, diabetes, heart disease, and liver disease. But there is limited scientific research to support these and other uses.

    How does it work?

    Nicotinamide riboside is changed in the body to a chemical called NAD+. The body needs NAD+ to work normally. Low levels of NAD+ can cause medical problems. Taking nicotinamide riboside can help raise these low NAD+ levels.

    NICOTINAMIDE RIBOSIDE Uses & Effectiveness What is this?

    Insufficient Evidence for:

    • High cholesterol. Taking nicotinamide riboside does not seem to lower total cholesterol or "bad" cholesterol (low-density lipoprotein or LDL cholesterol) in men with high cholesterol.
    • High blood pressure. Taking nicotinamide riboside seems to slightly reduce blood pressure. The effect seems to be greatest in people with high blood pressure.
    • Obesity. Taking nicotinamide riboside does not seem to improve body weight, cholesterol levels, or markers of diabetes in obese men.
    • Alzheimer disease.
    • Diabetes.
    • Heart disease.
    • Liver disease.
    • An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD).
    • Others.
    More evidence is needed to rate the effectiveness of nicotinamide riboside for these uses.

    NICOTINAMIDE RIBOSIDE Side Effects & Safety

    When taken by mouth: Nicotinamide riboside is POSSIBLY SAFE when used short-term. Side effects of nicotinamide riboside are usually mild. Side effects may include stomach problems such as nausea and bloating or skin problems such as itching and sweating too much.

    Special Precautions & Warnings:

    Pregnancy and breast-feeding: There isn't enough reliable information to know if nicotinamide riboside is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

    NICOTINAMIDE RIBOSIDE Interactions What is this?

    We currently have no information for NICOTINAMIDE RIBOSIDE Interactions


    The appropriate dose of nicotinamide riboside depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for nicotinamide riboside. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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    Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

    This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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