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    OLEIC ACID

    Other Names:

    18:1 n-9, 9-Octadecenoic Acid, Cis-9-Octadecenoic Acid, (9Z)-Octadec-9-Enoic Acid, Octadec-9-Enoic Acid, Octadecenoic Acid.

    OLEIC ACID Overview
    OLEIC ACID Uses
    OLEIC ACID Side Effects
    OLEIC ACID Interactions
    OLEIC ACID Dosing
    OLEIC ACID Overview Information

    Oleic acid is an omega-9 fatty acid. It can be made by the body. It is also found in foods. Highest levels are found in olive oil and other edible oils.

    Oleic acid is most commonly used for preventing heart disease and reducing cholesterol. It is also used for preventing cancer and other conditions, but there is no good scientific evidence to support these other uses.

    Don't confuse oleic acid with diets and oils containing oleic acid, such as the Mediterranean diet, olive oil, and canola oil or sunflower oil made to have higher levels of oleic acid. See separate listings for these topics.

    How does it work?

    Oleic acid is a type of fatty acid. Oils with oleic acid are used to replace saturated fats in the diet. Oleic acid might improve heart conditions by lowering cholesterol and reducing inflammation.

    OLEIC ACID Uses & Effectiveness What is this?

    Possibly Effective for:

    • Heart disease. Using cooking oils that provide about 20 grams (1.5 tablespoons) of oleic acid in place of dietary fats with higher amounts of saturated fat might reduce the risk of heart disease. But research is limited.
    • High cholesterol. Using cooking oils rich in oleic acid might help lower cholesterol. These oils include olive oil, some sunflower oils, and canola oil.

    Insufficient Evidence for:

    • Bladder cancer. People with higher blood levels of oleic acid seem to have a lower risk of bladder cancer. But the amount of oleic acid in the blood can be affected by more than just intake from foods. So, it's still unclear if increasing intake of oleic acid from food reduces bladder cancer risk. It's also unknown if oleic acid supplements can help prevent bladder cancer.
    • Breast cancer. Eating more foods that contain oleic acid doesn't seem to prevent breast cancer. It's unknown if oleic acid supplements can help prevent bladder cancer.
    • Diabetes. Following a low-fat diet that includes food with oleic acid doesn't seem to lower cholesterol in people with diabetes.
    • Diarrhea. Taking oleic acid might reduce the number of bowel movements in some people with diarrhea. But more research is needed.
    • High blood pressure. Eating oil high in oleic acid might not help to lower high blood pressure. But more research is needed.
    • Obesity. Some early research shows that using cooking oil containing oleic acid reduces fat around the abdomen by a small amount in people who are obese. It also seems to help to lower cholesterol in some people who are obese and at risk for heart disease. But using similar cooking oils without oleic acid also seem to have benefit. So, it's unclear if the oleic acid causes these improvements.
    • Pancreatic cancer. People who get more oleic acid from their diet may have a lower risk of pancreatic cancer. But not all research agrees.
    • Poor nutrient absorption that occurs when part of the small intestine is missing or removed (short bowel syndrome). Early research shows that taking oleic acid doesn't reduce diarrhea or help with nutrient absorption in people with short bowel syndrome.
    • Stroke. People with higher blood levels of oleic acid seem to have a lower risk of stroke. But the amount of oleic acid in the blood can be affected by more than just intake from foods. So, it's still unclear if increasing intake of oleic acid from food reduces stroke risk. It's also unknown if oleic acid supplements can help prevent bladder cancer.
    • A type of inflammatory bowel disease (ulcerative colitis). People who get more oleic acid from their diet might have a lower risk of ulcerative colitis. But not all research agrees.
    • Rapid gastric emptying (dumping syndrome).
    • Build up of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD).
    More evidence is needed to rate the effectiveness of oleic acid for these uses.

    OLEIC ACID Side Effects & Safety

    When taken by mouth: Oleic acid is LIKELY SAFE when used in food amounts. There isn't enough reliable information to know if oleic acid is safe when taken by mouth as a medicine.

    Special Precautions & Warnings:

    Pregnancy and breast-feeding: There isn't enough reliable information to know if oleic acid is safe to use as a medicine when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

    OLEIC ACID Interactions What is this?

    We currently have no information for OLEIC ACID Interactions

    OLEIC ACID Dosing

    The following doses have been studied in scientific research:

    ADULTS

    BY MOUTH:

    • For heart disease: Using cooking oils that provide 20 grams (1.5 tablespoons) of oleic acid per day in place of other saturated fats and oils has been used.
    • For high cholesterol: Cooking oils that contain high amounts of oleic acid in place of other saturated fats and oils has been used.

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    Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

    This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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