RUTIN Overview Information
Rutin is a plant pigment (flavonoid) that is found in certain fruits and vegetables. Rutin is used to make medicine. The major sources of rutin for medical use include buckwheat, Japanese pagoda tree, and Eucalyptus macrorhyncha. Other sources of rutin include the leaves of several species of eucalyptus, lime tree flowers, elder flowers, hawthorn leaves and flowers, rue, St. John's Wort, Ginkgo biloba, apples, and other fruits and vegetables.
Some people believe that rutin can strengthen blood vessels, so they use it for varicose veins, internal bleeding, hemorrhoids, and to prevent strokes due to broken veins or arteries (hemorrhagic strokes). Rutin is also used to prevent a side effect of cancer treatment called mucositis. This is a painful condition marked by swelling and ulcer formation in the mouth or lining of the digestive tract.
In combination with the proteins trypsin and bromelain, rutin is also used for osteoarthritis.
Rutin is sometimes used on the skin to reduce wrinkles.
How does it work?
Rutin has chemicals that might have antioxidant and anti-inflammatory effects. These chemicals might offer some protection against cancer and other diseases.
Possibly Effective for:
- Osteoarthritis. Taking rutin by mouth in combination with trypsin and bromelain (Wobenzym PS) seems to be about as effective as the medication diclofenac (Voltaren) in relieving pain and improving knee function in people with osteoarthritis.
- Swelling in the arm after breast surgery (post-surgical lymphedema). Some early research suggests that taking a specific product (Wobenzym N) containing rutin, pancreatin, papain, trypsin, and chymotrypsin daily for 7 weeks reduces swelling in the arm due to breast removal surgery.
- Aging skin. Early research suggests applying a cream containing rutin to the skin twice a day reduces the size and number of wrinkles and 'crow's feet' under the eyes.
- Blood vessel disease.
- Varicose veins.
- Prevention of mouth ulcers associated with cancer treatments.
RUTIN Side Effects & Safety
Rutin is LIKELY SAFE when taken by mouth in amounts found in fruits and vegetables. Rutin is POSSIBLY SAFE when taken by mouth appropriately in medicinal amounts for a short period of time or when applied on the skin. It can cause some side effects including headache, flushing, rashes, or stomach upset.
Special Precautions & Warnings:Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking rutin if you are pregnant or breast feeding. Stay on the safe side and avoid use.
The following doses have been studied in scientific research:
- For osteoarthritis: A combination product (Wobenzym PS), providing 600 mg of rutin, 288 mg of trypsin, and 540 mg of bromelain in divided doses has been used.
- For swelling in the arm after breast surgery (post-surgical lymphedema): A specific product (Wobenzym N) containing rutin, pancreatin, papain, bromelain, trypsin, and chymotrypsin daily for 7 weeks has been used.