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3.6 Overall Rating

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Most voted positive review

159 People found this comment helpful

I initially started taking it with iron and vitamin B complex to help my complete blood count. What I do not like is how I need to take one tablet with food. I wish I could take it without. My blood has never been healthier though, and I always had anemia. Plus it really speeds up your metabolism and I seemed to have lost fat but muscle stayed. More energy, overall feeling better. Highly recommend...

Most voted negative review

19 People found this comment helpful

Using 15 mg. of 5-MTHF from Extrafolate-S. Only been using it for about two 1/2 weeks. DNA tests showed I was low in producing folate. I can't tell any difference so far. It is supposed to support my psychiatric medications.

Shared reviews and ratings

Age: 35-44 | On supplement for 1 to less than 2 years |
12/26/2014
Condition: Other
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

This doesn't give a reason of miscarriage or MTHFR as reasons for taking this treatment, but it's the real reason I did. I had 6 miscarriages, 5 of which were consecutive after having had 3 healthy children. I went to doctor after doctor finally being diagnosed with MTHFR. After an RE recommended folic acid (which is NOT the same as methylfolate - 2 different forms of vitamin B9), I discovered that made things worse. I did my own research and discovered methylfolate. I took this and the very next pregnancy was carried to full term with a healthy baby as a result. Not only that though - my chronic fatigue, depression, neurological issues, and memory loss all immediately and dramatically improved. Folic acid is synthetic and cheap - but it is not what the body uses. It has to convert it to methylfolate first. For those of us with MTHFR polymorphisms, this process is either partially or completely broken. Folic acid is not only useless to us, it is actually deadly. I wish someone had told me years ago all I needed was a better vitamin B9!!Read More Read Less

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adallen | Age: 45-54 | On supplement for 1 to 6 months |
10/8/2014
Condition: Fatigue
Overall rating 4.3
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Age: 55-64 | On supplement for less than 1 month |
9/19/2014
Condition: Other
Overall rating 1.0
Effectiveness
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My wife takes Dylantin for epilepsy. She started taking folic acid about a week ago. This morning as we began our morning walk, she became dizzy and nauseous, to the point that we had to terminate our walk.

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anne | Age: 25-34 | On supplement for 1 to 6 months |
9/13/2014
Condition: Other
Overall rating 2.0
Effectiveness
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Satisfaction
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folic acid | Age: 35-44 | On supplement for 1 to 6 months |
8/5/2014
Condition: Other
Overall rating 3.0
Effectiveness
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one ear still block

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middlecystr | Age: 55-64 | On supplement for 1 to 6 months |
7/29/2014
Condition: Other
Overall rating 3.7
Effectiveness
Ease of Use
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My doctor added this supplement to my antidepressant (Pristique)to help with depression; as the Pristique just "kept my head above water" adding L-Methylfolate calcium 15 mg daily truly helps. My head definitely feels much improved. My energy level also has improved. However, I blame this supplement on huge amount of weight gain (10 lbs) in seven (7) weeks. Have not seen weight gain mentioned in any reviews. Could be just me, but 10 extra pounds is enough to keep me depressed. Hence the one star rating for not satisfied. Read More Read Less

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winnie | On supplement for 1 to 6 months |
6/24/2014
Condition: Cancer
Overall rating 4.0
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just want to know the benefits

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morninglory | Age: 45-54 | On supplement for 1 to less than 2 years |
5/27/2014
Condition: Folate deficiency
Overall rating 2.0
Effectiveness
Ease of Use
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I think to call folic acid 'folate' as if they are the same thing is hugely misleading and dangerous to suggest they are the same thing. Folic Acid, which is a much cheaper supplement than folate should be converted to folate by the body, but for those of us with a genetic MTHFR mutation (30-50% of the population!), taking folic acid is dangerous because we cannot convert it. Real folate is necessary in dealing with an MTHFR mutation and the long list of symptoms that stem from it: depression, fatigue, diabetes, cancers, chronic pain, etc. Read More Read Less

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Age: 35-44 | On supplement for 1 to less than 2 years |
5/8/2014
Condition: Other
Overall rating 5.0
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I'm pregnant and take 400 mg a day. They suggest taking more, but I eat a lot of foods that are high in Folic Acid and don't want to take too much.

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cathyde | Age: 75 or over | On supplement for 1 to 6 months |
2/22/2014
Condition: Restless legs syndrome (RLS)
Overall rating 3.0
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foad1 | Age: 55-64 | On supplement for less than 1 month |
2/11/2014
Condition: Other
Overall rating 2.3
Effectiveness
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1 400mcg pill a day

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Age: 13-18 | On supplement for less than 1 month |
2/2/2014
Condition:
Overall rating 5.0
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Eye-Folate from Global Healthcare Focus. It's a miracle!

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mary |
12/28/2013
Condition: Other
Overall rating 3.0
Effectiveness
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just started taking today

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Age: 65-74 | On supplement for less than 1 month |
12/27/2013
Condition: Lung cancer
Overall rating 3.3
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doinggood | Age: 35-44 | On supplement for 1 to 6 months |
12/25/2013
Condition: Other
Overall rating 4.0
Effectiveness
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Satisfaction

Very helpful in depression. Noticed a change one day after taking 15mg Deplin (L-5 Methyl-hydrotetrafolate, calcium salt). Day after taking the second tablet was the best I had since I can remember. Euphoric effects leveled off after about one week. After 3 months of treatment, I am far less depressed and anxious than I was before starting Deplin.

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Age: 65-74 | On supplement for 1 to 6 months |
12/23/2013
Condition: Folate deficiency
Overall rating 4.3
Effectiveness
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Satisfaction

the dreaded weight gain......been on this preszcribed medicaton for a little over a month and have gained almost 4 pounds......

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ane67 | Age: 75 or over | On supplement for 5 to less than 10 years |
12/1/2013
Condition: Ulcerative colitis
Overall rating 4.7
Effectiveness
Ease of Use
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cassie | Age: 13-18 | On supplement for 2 to less than 5 years |
11/10/2013
Condition: Fatigue
Overall rating 4.7
Effectiveness
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it helped me to stay focus in school and my studies. i can now walk and go out to big events without worrying about blackouts and headaches

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? | Age: 55-64 | On supplement for 1 to 6 months |
10/16/2013
Condition: Other
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

Acedemic

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tierra cook | Age: 55-64 | On supplement for 1 to less than 2 years |
9/27/2013
Condition:
Overall rating 5.0
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