Reviewer: Dennis, 65-74 on Treatment for 1 to less than 2 years (Consumer)

Comment:
This article is very poorly written, misleading, and out of date. This article seriously needs a complete rewrite. It conflates K1 with K2. While the two are chemically similar, their physiological functions are very different. It should be noted that 'K' equates only to 'K1' and not to 'K2'. K2 functions in the activation process of proteins which contain glutamate residue ... Show Full Comment

Comment:
This article is very poorly written, misleading, and out of date. This article seriously needs a complete rewrite. It conflates K1 with K2. While the two are chemically similar, their physiological functions are very different. It should be noted that 'K' equates only to 'K1' and not to 'K2'. K2 functions in the activation process of proteins which contain glutamate residues, allowing gamma carboxylation of these sites which then serve as calcium transporter proteins like MGP and Calcitonin (BGP) which are critical for appropriate calcium utilization. K2 is not used in the blood clotting mechanism; that is the role of K1. K2 is very safe to use without side effects and is used in Japan at the rate of 45mg/day to treat osteoporosis by the mechanism of BGP activation.
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Reviewer: Salutary Effects, 55-64 on Treatment for 1 to 6 months (Consumer)

Comment:
My Dr. had recommended 1000 daily D3. After a month's interval, I had a strong urgency to go to the bathroom. This is not presumed to be entirely normal, so I assumed that this was for me a normal metabolic outcome. I then tried vitamin K2 in supplement form, which I found to lower the heart rate and blood pressure. But after a time, about 6 weeks, just 100mcg a day caused restless muscul ... Show Full Comment

Comment:
My Dr. had recommended 1000 daily D3. After a month's interval, I had a strong urgency to go to the bathroom. This is not presumed to be entirely normal, so I assumed that this was for me a normal metabolic outcome. I then tried vitamin K2 in supplement form, which I found to lower the heart rate and blood pressure. But after a time, about 6 weeks, just 100mcg a day caused restless muscular reactions in my legs. I switched to 30mcg K2/25 IU MCT Oil Base Sublingual when required. This was a significant improvement over the supplements, and I was required to administer very judiciously just one tiny drop under the tongue. This sublingual strategy was so that the K2 goes direct into the blood stream and not processed thru through the liver. I probably don't require very much of either K2 or D3 noting metabolic effects with supplements such as becoming constipated or having a strong urgency to pee or restless legs, and have probably filled out my requirement. Noted effects on stopping K2/D3 sublingual was mild heart palpitations, so I will continue in small, judicious amounts and carefully monitor. Would recommend Boron supplements according to dosage recommendations, or perhaps Potassium Gluconate as they take far longer to fill out the basic requirement. I liken K2 to magnesium, as they both take only several weeks to fill out the requirement before noted metabolic effects.
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Reviewer: cookishoes, 35-44 on Treatment for 2 to less than 5 years (Consumer)

Comment:
Hi all, just making very very sure that you are well aware. If you are on warfarin or a similar blood thinner, BE VERY mindful of this supplement or foods or beverages that contain alot of Vitamin K!!!! It will counteract the blood thinner!! I had a blood clot and when they were trying to manage me (double blood thinners), I was not aware that green tea had K in it. Unfortunately, many Green, le ... Show Full Comment

Comment:
Hi all, just making very very sure that you are well aware. If you are on warfarin or a similar blood thinner, BE VERY mindful of this supplement or foods or beverages that contain alot of Vitamin K!!!! It will counteract the blood thinner!! I had a blood clot and when they were trying to manage me (double blood thinners), I was not aware that green tea had K in it. Unfortunately, many Green, leafy foods that ARE good for you are BAD if you suffer from blood clots or similar conditions!! Good luck and well wishes!!
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Reviewer: alogan458, 55-64 Female on Treatment for 1 to 6 months (Consumer)

Comment:
I have been taking K2 (as Menaquinone-7) (MK-7)(from Natto, fermented soy.) Vitamin K ,not K2, makes proteins for blood clotting, and is found in green leafy vegetables. K2 when combined with D3 increases bone formation and bone density. K and K2 are not the same. After many years of frustration with conventional medicine, I started researching my symptoms on line,( skin pain, joint pain, neuro ... Show Full Comment

Comment:
I have been taking K2 (as Menaquinone-7) (MK-7)(from Natto, fermented soy.) Vitamin K ,not K2, makes proteins for blood clotting, and is found in green leafy vegetables. K2 when combined with D3 increases bone formation and bone density. K and K2 are not the same. After many years of frustration with conventional medicine, I started researching my symptoms on line,( skin pain, joint pain, neuropathy, fatigue, weight gain, and more). My reading led me to vitamin D3 and more reading led me to believe I needed K2 to direct vitamins and minerals from my blood stream and into my bones. I went to see my family doctor to ask if she would check my D3 levels, as I intended on increasing my intake to see if it helped my symptoms. I have limped for well over a year due to Mortens neuroma in my left foot. Within a month of taking the D3-K2 combination I have stopped limping. My D3 levels are fine so I plan on increasing my dose to see if there will be more improvement. So far the only side effect is with the D3 (stomach ache, if taken without food.) No side effects with the K2. I feel better than I have in a long time, and hope more benefits are to come.
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Reviewer: JazzCool, 55-64 Female on Treatment for 2 to less than 5 years (Consumer)

Comment:
The article states that only K1 is available in the U.S. This is not true. I have bought K2 for many years. Either that part of the article is years out of date or the writer did very poor research into what is available in the U.S. That poor a quality of reporting reflects poorly on WebMD's reputation for good information.

Comment:
The article states that only K1 is available in the U.S. This is not true. I have bought K2 for many years. Either that part of the article is years out of date or the writer did very poor research into what is available in the U.S. That poor a quality of reporting reflects poorly on WebMD's reputation for good information.
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