CODONOPSIS

OTHER NAME(S):

Bastard Ginseng, Bellflower, Bonnet Bellflower, Campanule à Bonnet, Chuan Dang, Codonopsis Modestae, Codonopsis pilosula, Codonopsis Pilosula Modesta, Codonopsis tangshen, Codonopsis tubulosa, Dangshen, Deodeok, Dong Seng, Ginseng Bâtard, Ginseng du Pauvre, Racine de Campanule à Bonnet, Radix Codonopsis, Radix Codonopsis Pilosulae, Tsoong.

Overview

Overview Information

Codonopsis is an herb. People use the root to make medicine.

People use codonopsis for HIV/AIDS, protection against side effects of radiation treatment, heartburn, and other conditions, but there is no good scientific evidence to support these uses.

Codonopsis is sometimes used in commercial products as a substitute for ginseng. But none of the active chemicals in ginseng have been found in codonopsis.

How does it work?

Codonopsis contains chemicals that seem to slow down the growth of cancer cells. It also seems change the response of the immune system.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • HIV/AIDS.
  • Protection against side effects of radiation therapy.
  • Cancer.
  • Swelling (inflammation) of the main airways in the lung (bronchitis).
  • Cough.
  • Asthma.
  • Tuberculosis.
  • Obesity.
  • High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia).
  • Heartburn.
  • Diarrhea.
  • Diabetes.
  • Anorexia.
  • Other conditions.
More evidence is needed to rate the effectiveness of codonopsis for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Codonopsis is POSSIBLY SAFE for most people in appropriate amounts. Doses of 6-9 grams of codonopsis seem to be safe based on traditional use. But codonopsis is POSSIBLY UNSAFE in large amounts. Doses of 30-60 grams of codonopsis have been linked with side effects including chest pain, throat pain, dizziness, confusion, and other symptoms.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if codonopsis is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Codonopsis might slow blood clotting and increase bleeding. In theory, taking codonopsis might make bleeding disorders worse.

Cross-allergies: People allergic to mugwort, carrots, and celery might also have an allergic reaction to codonopsis. Use codonopsis with caution if you are allergic to one of these plants.

Surgery: Codonopsis might slow blood clotting. In theory, taking codonopsis might increase the risk for bleeding during and after surgical procedures. Stop using codonopsis at least two weeks before a scheduled surgery.

Interactions

Interactions?

We currently have no information for CODONOPSIS Interactions.

Dosing

Dosing

The appropriate dose of codonopsis depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for codonopsis. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Lee, K. T., Choi, J., Jung, W. T., Nam, J. H., Jung, H. J., and Park, H. J. Structure of a new echinocystic acid bisdesmoside isolated from Codonopsis lanceolata roots and the cytotoxic activity of prosapogenins. J Agric.Food Chem 7-17-2002;50(15):4190-4193. View abstract.
  • Lee, K. W., Jung, H. J., Park, H. J., Kim, D. G., Lee, J. Y., and Lee, K. T. Beta-D-xylopyranosyl-(1-->3)-beta-D-glucuronopyranosyl echinocystic acid isolated from the roots of Codonopsis lanceolata induces caspase-dependent apoptosis in human acute promyelocytic leukemia HL-60 cells. Biol Pharm Bull. 2005;28(5):854-859. View abstract.
  • Wang, Z. T., Du, Q., Xu, G. J., Wang, R. J., Fu, D. Z., and Ng, T. B. Investigations on the protective action of Condonopsis pilosula (Dangshen) extract on experimentally-induced gastric ulcer in rats. Gen.Pharmacol 1997;28(3):469-473. View abstract.
  • Wang, Z. T., Ng, T. B., Yeung, H. W., and Xu, G. J. Immunomodulatory effect of a polysaccharide-enriched preparation of Codonopsis pilosula roots. Gen.Pharmacol 1996;27(8):1347-1350. View abstract.
  • Xu, X., Wang, S. R., and Lin, Q. [Clinical and experimental study on codonopsis pilosula oral liquor in treating coronary heart disease with blood stasis]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1995;15(7):398-400. View abstract.
  • Du YE, Lee JS, Kim HM, et al. Chemical constituents of the roots of Codonopsis lanceolata. Arch Pharm Res. 2018;41(11):1082-1091. View abstract.
  • Hur GY, Choi GS, Park HJ, Ye YM, Park HS. Anaphylactic shock induced by Codonopsis lanceolata, traditional Chinese medicine in a patient with allergic rhinitis. Allergy. 2008;63(10):1406-7. View abstract.
  • Lee J, Shibamoto T, Ha J, Jang HW. Identification of volatile markers for the detection of adulterants in red ginseng (Panax ginseng) juice using headspace stir-bar sorptive extraction coupled with gas chromatography and mass spectrometry. J Sep Sci. 2018. View abstract.
  • Luan YP, Li QF, Wu SG, Mao DC, Deng YY, Chen RW. Tsoong induces apoptosis and inhibits proliferation, migration and invasion of pancreatic ductal adenocarcinoma cells. Mol Med Rep. 2018;17(3):3527-3536. View abstract.
  • Reid D. A handbook of Chinese healing herbs. Boston, MA:Shambhala, 1995.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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