CADE

OTHER NAME(S):

Alquitran de Enebro, Cada, Cade Essential Oil, Cade Juniper, Cade Leaf, Cade Oil, Cade Stem, Cade Wood, Cade Wood Essential Oil, Cade Wood Oil, Common Juniper, Essence de Cade, Feuille de Cade, Genévrier Cade, Genévrier Epineux, Genévrier Oxycèdre, Goudron de Cade, Huile de Cade, Huile Essentielle de Cade, Juniper Tar, Juniper Tar Oil, Juniperus oxycedrus, Kade, Kadeoel, Kade Oil, Oil of Cade, Oil of Juniper Tar, Oleum Cadinum, Oleum Juniperi Empyreumaticum, Oxycèdre, Pix Cadi, Pix Juniper, Pix Oxycedri, Plum Juniper, Prickly Cedar, Prickly Juniper, Pyroleum Juniperi, Pyroleum Oxycedri, Redtified Cade Oil, Red-Berry Juniper, Sharp Cedar, Wacholderteer.<br/><br/>

Overview

Overview Information

Cade is a plant. The leaf, berries, stem, and oil extracted from the wood are used for medicine. The oil is also commonly used as a fragrance in perfumes, skin creams, and other products.

Cade oil is taken by mouth or applied to the skin for many different uses, but there is no good scientific research to support the use of cade oil for any medical condition.

How does it work?

Some studies in the lab show that cade extracts can kill bacteria, decrease swelling (inflammation), and improve blood sugar levels. There isn't enough information to know if cade has these effects in people.

Uses

Uses & Effectiveness?

Insufficient Evidence for



TAKEN BY MOUTH:

  • Diabetes.
  • Diarrhea.
  • Peptic ulcer disease (PUD).
  • High blood pressure.
  • Lung infections.
  • Common cold.
  • Kidney stones.
  • Cancer.
  • Psoriasis.
  • Eczema.
  • Scabies.
  • Wounds.
  • Head lice.
  • Dandruff.
  • Hair loss.
  • Cancers.
  • Snake bites.
  • Other conditions.
More evidence is needed to rate the effectiveness of cade for these uses.

Side Effects

Side Effects & Safety

Fully processed cade oil ("rectified cade oil") is LIKELY SAFE when applied to the skin in preparations containing 1% to 5% of the oil. These products seem to be safe to use short-term for minor skin problems.

But cade oil that has not been fully processed to remove cancer-causing compounds is LIKELY UNSAFE to take by mouth or apply to the skin. Avoid using it.

Fully processed cade oil ("rectified cade oil") is POSSIBLY UNSAFE when taken by mouth. It irritates the lining of the mouth and can cause serious side effects such as breathing problems, organ failure, seizures, and coma. Avoid use.

There isn't enough information to know if taking cade berries or leaf extracts is safe or what the possible side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of cade during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Children: Any preparations containing cade oil are LIKELY UNSAFE for children, either taken by mouth or when applied to the skin. Children seem to be at higher risk for serious, even deadly reactions to cade oil.

Cypress allergy: Pollen from cade trees can cause allergic reactions in people with cypress allergies.

Interactions

Interactions?

We currently have no information for CADE Interactions.

Dosing

Dosing

The appropriate dose of cade depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for cade. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Anon. Final report on the safety assessment of Juniperus communis Extract, Juniperus oxycedrus Extract, Juniperus oxycedrus Tar, Juniperus phoenicea extract, and Juniperus virginiana Extract. Int J Toxicol 2001;20:41-56. View abstract.
  • Angioni A, Barra A, Russo MT, et al. Chemical composition of the essential oils of Juniperus from ripe and unripe berries and leaves and their antimicrobial activity. J Agric Food Chem 2003;51:3073-8. View abstract.
  • Koruk, S. T., Ozyilkan, E., Kaya, P., Colak, D., Donderici, O., and Cesaretli, Y. Juniper tar poisoning. Clin.Toxicol.(Phila) 2005;43(1):47-49. View abstract.
  • Achour S, Abourazzak S, Mokhtari A, et al. Juniper tar (cade oil) poisoning in new born after a cutaneous application. BMJ Case Reports 2011 Oct 28;2011. View abstract.
  • Bello R, Moreno L, Beltra´n B, et al. Effects on arterial blood pressure of methanol and dichloromethanol extracts from Juniperus oxycedrus L. Phytother Res 1997;11(2):161-2.
  • Code of Federal Regulations, Title 21, chapter 1, subchapter D, part 346, subpart B (21CFR346.16). Anorectal drug products for over-the-counter human use - Analgesic, anesthetic, and antipruritic active ingredients.
  • Hanène M, Ameur E, Larbi KM, et al. Chemical composition of the essential oils of the berries of Juniperus oxycedrus L. ssp. rufescens (L. K.) and Juniperus oxycedrus L. ssp. macrocarpa (S. &amp; m.) Ball. and their antioxidant activities. Nat Prod Res 2012;26(9):810-20. View abstract.
  • Iacovacci P, Afferni C, Barletta B, et al. Juniperus oxycedrus: a new allergenic pollen from the Cupressaceae family. J Allergy Clin Immunol 1998;101:755-61. View abstract.
  • Karaman I, Sahin F, Gulluce M, et al. Antimicrobial activity of aqueous and methanol extracts of Juniperus oxycedrus L. J Ethnopharmacol 2003;85:231-5. View abstract.
  • Moreno L, Bello R, Beltran B, et al. Pharmacological screening of different Juniperus oxycedrus L. extracts. Pharmacol Toxicol 1998;82:108-12. View abstract.
  • Orhan N, Aslan M, Demirci B, Ergun F. A bioactivity guided study on the antidiabetic activity of Juniperus oxycedrus subsp. oxycedrus L. leaves. J Ethnopharmacol 2012;140(2):409-15. View abstract.
  • Orhan N, Aslan M, Pekcan M, et al. Identification of hypoglycaemic compounds from berries of Juniperus oxycedrus subsp. oxycedrus through bioactivity guided isolation technique. J Ethnopharmacol 2012;139(1):110-8. View abstract.
  • Prudden JF, Balassa LL. The biological activity of bovine cartilage preparations. Clinical demonstration of their potent anti-inflammatory capacity with supplementary notes on certain relevant fundamental supportive studies. Semin Arthritis Rheum 1974;3:287-321.
  • Rahmani H, Leonhardt S, Beladdale D, et al. Severe acute lung oedema after rectal enema with cade oil (abstract). European Association of Poisons Centres and Clinical Toxicologists XXIV International Congress, Strasbourg, 2004. Clin Toxicol 2004;42(4):487.
  • Salido S, Altarejos J, Nogueras M, et al. Chemical studies of essential oils of Juniperus oxycedrus ssp. badia. J Ethnopharmacol 2002;81:129-34. View abstract.
  • Skalli S, Chebat A, Badrane N, Bencheikh RS. Side effects of cade oil in Morocco: an analysis of reports in the Moroccan herbal products database from 2004 to 2012. Food Chem Toxicol 2014;64:81-5. View abstract.
  • Tavares L, McDougall GJ, Fortalezas S, et al. The neuroprotective potential of phenolic-enriched fractions from four Juniperus species found in Portugal. Food Chem 2012;135(2):562-70. View abstract.
  • Taviano MF, Marino A, Trovato A, et al. Antioxidant and antimicrobial activities of branches extracts of five Juniperus species from Turkey. Pharm Biol 2011;49(10):1014-22. View abstract.
  • Taviano MF, Marino A, Trovato A, et al. Juniperus oxycedrus L. subsp. oxycedrus and Juniperus oxycedrus L. subsp. macrocarpa (Sibth. & Sm.) Ball. "berries" from Turkey: comparative evaluation of phenolic profile, antioxidant, cytotoxic and antimicrobial activities. Food Chem Toxicol 2013;58:22-9. View abstract.
  • Tisserand R, Young R. Essential Oil Safety: A Guide for Healthcare Professionals. 2nd edition, 2014. Churchill Livingstone Elsevier, UK, pg.222-3.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.