Oral contraceptives manage levels of estrogen and progestin, which make your menstrual periods shorter and lighter. That often eases the pain of endometriosis. Your doctor may prescribe pills to be taken continuously, with no breaks for a menstrual period, or progestin-only therapy. Progestin-only therapy can also be given as a shot, or via birth control patches, vaginal rings, or intrauterine devices (IUDs). Endometriosis symptoms may return after you go off the birth control.