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    Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

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    Topic Overview

    Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce fever and inflammation and relieve pain. Examples of NSAIDs include aspirin, ibuprofen, and naproxen.

    Be sure to follow the nonprescription medicine precautions. Always take these medicines exactly as prescribed or according to the label.

    Ibuprofen (such as Motrin or Advil)

    • Adults: The initial dose is 400 mg. Follow-up doses are 200 mg to 400 mg every 4 hours as needed, up to a maximum of 4 doses in a 24-hour period.
    • Children: Check with your child's doctor if your child is less than 6 months old or less than 12 pounds. Dosages are based on the child's weight. Give follow-up doses every 6 hours as needed, up to a maximum of 4 doses in a 24-hour period.
      • Talk to your doctor before you give medicine to reduce a fever in a baby who is 3 months of age or younger. This is to make sure a young baby's fever is not a sign of a serious illness. The exception is if your baby has just had an immunization. Fevers sometimes occur as a reaction to immunizations. After immunizations, you can give your baby medicine to reduce a fever.
    Ibuprofen dose for your child's weight
    Child's weight in pounds (lb) Child's weight in kilograms (kg) Dose
    Less than 12 lb Less than 6 kg Ask a doctor
    12-17 lb 7-8 kg 50 mg
    18-23 lb 9-10 kg 75 mg
    24-35 lb 11-16 kg 100 mg
    36-47 lb 17-21 kg 150 mg
    48-59 lb 22-27 kg 200 mg
    60-71 lb 28-32 kg 250 mg
    72-95 lb 33-43 kg 300 mg
    96 lb and above 44 kg and above Adult dose

    Naproxen (such as Aleve)

    • Adults: Initial dose is 440 mg. Follow-up doses are 220 mg every 8 to 12 hours as needed. Drink a full glass of water with each dose. Do not take more than 440 mg in any 8-hour to 12-hour period or 660 mg in a 24-hour period.
    • Adults older than 65: Do not take more than 220 mg every 12 hours unless your doctor tells you to.
    • Children: Do not give naproxen to children younger than 12 unless your doctor tells you to. Your doctor may prescribe naproxen for your child.
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    WebMD Medical Reference from Healthwise

    Last Updated: November 14, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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