Uremia (uremic syndrome) is a serious complication of
chronic kidney disease and
acute kidney injury (also known as acute renal failure). It occurs when
urea and other waste products build up in the body
because the kidneys are unable to eliminate them. These substances can become
poisonous (toxic) to the body if they reach high levels.
Prolonged or severe fluid buildup (edema) may make the uremic
Uremic syndrome may affect any part of the body and can cause: