Skip to content

Uremia

Font Size

Topic Overview

Uremia (uremic syndrome) is a serious complication of chronic kidney disease and acute kidney injury (also known as acute renal failure). It occurs when urea and other waste products build up in the body because the kidneys are unable to eliminate them. These substances can become poisonous (toxic) to the body if they reach high levels.

Prolonged or severe fluid buildup (edema) may make the uremic syndrome worse.

Uremic syndrome may affect any part of the body and can cause:

  • Nausea, vomiting, loss of appetite, and weight loss.
  • Changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma.
  • Abnormal bleeding, such as bleeding spontaneously or profusely from a very minor injury.
  • Heart problems, such as an irregular heartbeat, inflammation in the sac that surrounds the heart (pericarditis), and increased pressure on the heart.
  • Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion).

Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored.

1

WebMD Medical Reference from Healthwise

Last Updated: August 29, 2013
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Hot Topics

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

feet
Solutions for 19 types.
MS Overview
Recognizing symptoms.
pregnancy test and calendar
Helping you get pregnant.
man rubbing painful knee
A visual guide.
lone star tick
How to identify that bite.
woman standing behind curtains
How it affects you.
brain scan with soda
Tips to avoid complications.
row of colored highlighter pens
Tips for living better.
human lungs
Symptoms, causes, treatments.
woman dreaming
What Do Your Dreams Say About You?
two male hands
Test your knowledge.

Women's Health Newsletter

Find out what women really need.