When you have a gout attack, a non-steroidal anti-inflammatory medicine (NSAID) like ibuprofen (Advil, Motrin) might help with the pain. Your health care provider also may give you a prescription for a stronger NSAID; steroids (like prednisone); or a drug called colchicine to have on hand in case of a gout attack.
Taking aspirin, however, can be a bad idea. Aspirin can cause your uric acid levels to increase, which can bring on a gout flare or make a flare worse. Other medicines, such as diuretics (water pills) and cyclosporine, also can trigger a flare. That’s why it’s important that your rheumatologist knows about all your medications and that all your doctors know you have gout -- especially if they're going to start you on new medications.