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Breast Cancer Health Center

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Breast Cancer and Biopsy

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If your doctor finds something questionable during a routine breast exam, screening mammogram, or ultrasound, she may recommend you have a breast biopsy.

What Is It?

Doctors remove cells or tissue from the area in question to examine under a microscope. It’s the only way to know for sure if a potential trouble spot is cancer.

There are different breast biopsy procedures. The method your doctor recommends will depend on:

  • How large your breast lump or suspicious area is
  • Where it’s located
  • If there’s more than one abnormal area
  • If you have any other medical problems
  • Your personal preferences

Types of Breast Biopsies

Fine-needle aspiration. A small needle is used to take a sample of cells from the area in question. If the lump is a cyst (a fluid-filled sac), the procedure may cause it to collapse. This fluid will be looked at under a microscope for any signs of cancer. If the lump is solid, cells can be smeared onto slides for examination.

Core biopsy. A larger needle is used to remove a sample of the tissue. The types of this procedure include:

  • Ultrasound-guided core biopsy. A needle is placed into the breast tissue. Ultrasound helps confirm the exact location of the potential trouble spot so the needle is placed correctly. Tissue samples are then taken through the needle. Ultrasound can see the difference between cysts and solid lesions.
  • Stereotactic biopsy. You'll be helped into a position that centers the area to be tested in the window of a specially designed instrument. Mammogram films called SCOUT films are taken so the radiologist can examine the area to be biopsied. Using a local anesthetic, the radiologist makes a small opening in the skin. A needle is placed into the breast tissue, and computerized pictures help confirm the exact placement. Tissue samples are taken through the needle. It's common for the medical professionals to take multiple tissue samples (about three to five).

Open excisional biopsy. This is surgery to remove an entire lump. The tissue is then studied under a microscope. If a section of normal breast tissue is taken all the way around a lump (called a lumpectomy), the biopsy is also considered a breast cancer treatment. In this technique, a wire is put through a needle into the area to be biopsied. An X-ray helps make sure it’s in the right place, and a small hook at the end of the wire keeps it in position. The surgeon uses this wire as a guide to locate the suspicious tissue.

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