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Modified Radical Mastectomy

When doctors treat breast cancer, their goal is to remove all of the cancer -- or as much of it as possible. Surgery is one of the mainstays of treatment, and today a procedure called modified radical mastectomy (MRM) has become a standard surgical treatment for early-stage breast cancers.

Modified radical mastectomy is especially helpful for early-stage breast cancer that has spread to the lymph nodes. Studies show that MRM is just as effective as radical mastectomy, but not nearly as disfiguring.  MRM spares one or both of the chest muscles, preventing an unsightly hollow in the chest that is common after a traditional radical mastectomy.

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Treatment of triple-negative breast cancer may include the following: Chemotherapy followed by surgery (breast-conserving surgery, total mastectomy, or modified radical mastectomy) and lymph node dissection. A clinical trial of combination chemotherapy with drugs that are often used to treat breast cancer and drugs that are not usually used to treat breast cancer. A clinical trial of PARP inhibitor therapy. Check for U.S. clinical trials from NCI's list of cancer clinical trials...

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What Is Modified Radical Mastectomy?

During a modified radical mastectomy, the surgeon removes the breast (including the skin, breast tissue, areola, and nipple) and most of the lymph nodes under the arm. The lining over the large muscle in the chest called the pectoralis major is also removed. However, this surgery spares the pectoralis major muscle itself.

MRM surgery tries to preserve enough healthy tissue and skin for a surgeon to perform breast reconstruction surgery in women who want to have it done.

What to Expect During an MRM

A modified radical mastectomy takes about two to four hours. The surgery might take longer if you have breast reconstruction surgery done immediately afterward.

While you are under general anesthesia, the surgeon will make a single incision across one side of the chest. The skin will be pulled back. Then the doctor will remove the entire breast tissue, the lining over the pectoralis major, as well as some of the lymph nodes under your arm.  Finally, the doctor will close the incision.

The goal is to remove the cancer while preserving as much of the skin and tissue as possible so that you can have breast reconstruction. The surgeon also will try to avoid damaging nearby blood vessels and nerves.

Although research has found modified radical mastectomy to be generally safe and effective, like all surgical procedures it can have risks, which include:

  • Bleeding
  • Infection
  • Swelling of the arm
  • Pockets of fluid forming underneath the incision (seromas)
  • Risks from general anesthesia

Some people experience numbness in the upper arm, which is caused by damage to small nerves in the area where the lymph nodes are removed. There is a good chance that you will regain most of the feeling in your arm over time.

The lymph nodes that are removed will be sent to a lab for examination to determine whether the cancer has spread.

After a Modified Radical Mastectomy

Once your surgery is complete, you will need to stay in the hospital for one or two nights. Thin plastic tubes will be placed in your breast area to drain off any fluid. These drains are attached to small suction devices. The drains will be removed about a week after your surgery. The hospital staff will show you how to care for the tubes until they are removed.

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