Radiation therapy typically involves using a large machine called a linear accelerator to deliver precise amounts of high-energy radiation to kill cancer cells. The radiation stops the reproduction of cancer cells while minimizing damage to healthy tissues. Radiation therapy has been shown to improve survival in women with breast cancer.
Triple-negative breast cancer (TNBC) is defined as the absence of staining for estrogen receptor, progesterone receptor, and HER2/neu. TNBC is insensitive to some of the most effective therapies available for breast cancer treatment including HER2-directed therapy such as trastuzumab and endocrine therapies such as tamoxifen or the aromatase inhibitors. Combination cytotoxic chemotherapy administered in a dose-dense or metronomic schedule remains the standard therapy for early-stage TNBC. A prospective...
Radiation therapy is painless. However, some women experience side effects, which can include:
Redness, discomfort, and dryness of the skin in the treated area. Your doctor will recommend a specific treatment if this happens. The redness can take as long as a year to fade.
Fatigue, usually starting two to three weeks after treatment begins. The fatigue increases during the duration of treatment and goes away about a month after treatment ends. Fatigue should not disable you. Most women cope by taking a nap or by going to bed earlier.
Reduced blood counts. Your blood will be checked regularly, especially if you are also receiving chemotherapy.
Sometimes women also experience a sore mouth or throat, or dry mouth, if these areas are irradiated.