Pituitary adenomas can be classified according to staining affinities of the cell cytoplasm,size,endocrine activity,histologic characteristics,hormone production and contents,ultrastructural features,granularity of the cell cytoplasm,cellular composition,cytogenesis,and growth pattern.[ 1 ] Recent classifications,however,omit criteria based on tinctorial stains (i.e.,acidophilic,...
Incidence and Mortality About 7% of all malignancies in children under the age of 15 are neuroblastomas. About one quarter of cancers in the first year of life are neuroblastomas,making this the most frequent histological type of infant cancer.[ 1,2 ] The incidence rate of the disease in children younger than 1 year is about 35 per million but declines rapidly with age to about 1 per million ...
Important It is possible that the main title of the report Astrocytoma, Malignant is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...
Important It is possible that the main title of the report Astrocytoma is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...
Treatment Option Overview
Many of the improvements in survival in childhood cancer have been made as a result of clinical trials that have attempted to improve on the best available,accepted therapy. Clinical trials in pediatrics are designed to compare new therapy with therapy that is currently accepted as standard. This comparison may be done in a randomized study of two treatment arms or by evaluating a single new ...
Treatment of Recurrent Childhood Ependymoma
Recurrence is not uncommon in both benign and malignant childhood brain tumors and may develop many years after initial treatment. For ependymoma,delays beyond 10 to 15 years have been reported.[ 1,2 ] Disease generally recurs at the primary tumor site,even in children with malignant ependymomas.[ 3,4 ] Systemic relapse is extremely rare. At time of relapse,a complete evaluation for ...
Important It is possible that the main title of the report Glioblastoma Multiforme is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...
Histopathologic Classification of Childhood Craniopharyngioma
Craniopharyngiomas are histologically benign and do not metastasize to remote brain locations or to areas outside the sellar region except by direct extension. They may be invasive,however,and may recur locally. They may be classified as adamantinomous or squamous papillary,with the former being the predominant form in children.[ 1 ] They are typically composed of both a solid portion with ...
Recurrent Childhood Brain Stem Glioma
Diffuse Intrinsic Pontine Gliomas Given the dismal prognosis for patients with diffuse intrinsic pontine glioma (DIPG),progression of the pontine lesion is anticipated generally within 1 year from initial radiation therapy. In most cases,biopsy at the time of clinical or radiologic progression is neither necessary nor recommended. To date,no salvage regimen has been shown to extend survival. ...
Untreated Childhood Brain Stem Glioma
Diffuse Intrinsic Pontine Gliomas Conventional treatment for children with diffuse intrinsic pontine glioma (DIPG) is radiation therapy to involved areas. Such treatment will result in transient benefit for most patients,but over 90% of patients will die within 18 months of diagnosis. The conventional dose of radiation therapy ranges between 5,400 cGy and 6,000 cGy given locally to the primary .