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Chickenpox Vaccine Not Responsible for Rise in Shingles, Study Says

39 percent increase over 18 years remains unexplained
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WebMD News from HealthDay

By Serena Gordon

HealthDay Reporter

MONDAY, Dec. 2, 2013 (HealthDay News) -- The prevalence of a painful condition known as shingles is increasing in the United States, but new research says the chickenpox vaccine isn't to blame.

Shingles is caused by the same virus that causes chickenpox, the varicella zoster virus. Researchers have theorized that widespread chickenpox vaccination since the 1990s might have given shingles an unintended boost. But that theory didn't pan out in a study of nearly 3 million older adults.

"The chickenpox vaccine program was introduced in 1996, so we looked at the incidence of shingles from the early '90s to 2010, and found that shingles was already increasing before the vaccine program started," said study author Dr. Craig Hales, a medical epidemiologist at the U.S. Centers for Disease Control and Prevention. "And as immunization coverage in children reached 90 percent, shingles continued at the same rate."

Once someone has had chickenpox, the varicella zoster virus stays in the body. It lies dormant for years, often even for decades, but then something happens to reactivate it. When it's reactivated, it's called herpes zoster or shingles.

Exposure to children with chickenpox boosts adults' immunity to the virus, Hales explained. But experts wondered if vaccinating a whole generation of children against chickenpox might affect the rate of shingles in older people, who have already been exposed to the chickenpox virus.

"Our immunity naturally wanes over time, and once it wanes enough, that's when the virus can reactivate," said Hales. "So, if we're never exposed to children with chickenpox, would we lose that normal immunity boost?"

To answer this question, Hales and his colleagues reviewed Medicare claims data from 1992 to 2010 that included about 2.8 million people over the age of 65.

They found that annual rates of shingles increased 39 percent over the 18-year study period. However, they didn't find a statistically significant change in the rate after the introduction of the chickenpox vaccine. They also found that the rate of shingles didn't vary from state to state where there were different rates of chickenpox vaccine coverage.

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