Skip to content

Read user comments about the side effects, benefits, and effectiveness of Diphenhydramine HCl Oral.

Overall User Ratings

177 Total User Reviews

User Reviews

1-5 of 149 Next»
Condition: Chronic Trouble Sleeping
1/30/2015 7:37:29 PM

Reviewer: Cnhinton123, 19-24 Male on Treatment for less than 1 month (Patient)

Effectiveness

Current Rating: 4

Ease of Use

Current Rating: 5

Satisfaction

Current Rating: 3

Comment:
This medicine has helped with my insomnia. However, I recently discovered from a recently released study that anticholinergics like this medicine increases the risk of developing Alzheimer's. I only take it when highly necessary- when my sleep schedule rotates (I have a circadian rhythm sleep disorder). I think it would be unwise to take it every night. This medicine also reduces my anxiety be ... Show Full Comment

Condition: Chronic Trouble Sleeping
10/14/2014 2:59:46 PM

Reviewer: MRG53, 55-64 Male on Treatment for 1 to less than 2 years (Patient)

Effectiveness

Current Rating: 5

Ease of Use

Current Rating: 5

Satisfaction

Current Rating: 5

Comment:
My issues aren't "chronic" but I do have periods where sleep eludes me. When those occur I take 1x 50mg gel cap ~9 hours before I have to wake up and it works quite well. IE my alarm goes off at 6a so if I take this I try to do so by ~9p otherwise I wake up a little groggy. NOTE: Allow 9-10 hours

Condition: Chronic Trouble Sleeping
5/31/2014 12:14:31 AM

Reviewer: Vincent, 55-64 Male on Treatment for 1 to 6 months (Patient)

Effectiveness

Current Rating: 5

Ease of Use

Current Rating: 5

Satisfaction

Current Rating: 5

Comment:
I'm 59 and starting to experience prolonged periods of time without sleep. Sometimes, I go three days without sleep, until finally, my body quits fighting it and I can sleep. Upon waking up, I feel miserable, tired, cranky and non-productive. I don't take medications of any kind unless it's an absolute emergency. However, prolonged periods without sleep were taking their toll on me. ... Show Full Comment

Condition: Chronic Trouble Sleeping
5/25/2014 12:56:10 PM

Reviewer: steff117, 55-64 Female on Treatment for 1 to 6 months (Patient)

Effectiveness

Current Rating: 3

Ease of Use

Current Rating: 5

Satisfaction

Current Rating: 4

Comment:
i have to take more than the 1 or 2 mentioned on the bottle. Severe side effects for me was dry mouth, and short term memory loss. I will get up to go and get something out of the kitchen and before I ever get to the door, I can't remember what I was going to get. Also, I have slight arthritis in my fingers, and when I take this medication at bedtime, it effects my handz.. I cannot open t ... Show Full Comment

Condition: Chronic Trouble Sleeping
5/23/2014 10:35:41 AM

Reviewer: 75 or over Male on Treatment for 6 months to less than 1 year (Patient)

Effectiveness

Current Rating: 4

Ease of Use

Current Rating: 4

Satisfaction

Current Rating: 3

Comment:
Take about 4 to 6 25mm tablets at night. Also take 2 Xanax tablets. Recently by morning is I have slept fairly well, I remain a bit dizzy.

1-5 of 149 Next»

Ask the pharmacist

Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
See the Ask the Pharmacist event schedule.

Ask a Question

Popular Slideshows & Tools on WebMD

disciplining a boy
Types, symptoms, causes.
psoriasis
What it looks like.
No gym workout
Moves to help control blood sugar.
acupuncture needle on shoulder
10 tips to look and feel good.
Epinephrine Injection using Auto-Injector Syringe
Life-threatening triggers.
chest x-ray
7 early symptoms.
woman biting a big ice cube
Habits that wreck your teeth.
Breast Cancer Overview
Symptoms and treatments.
embarrassed woman
Do you feel guilty after eating?
pacemaker next to xray
Treatment options.
caregiver with parent
10 tips for daily life.
birth control pills
Which kind is right for you?

Newsletters

Subscribe to free WebMD newsletters.

  • WebMD Daily

    WebMD Daily

    Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.

  • Men's Health

    Men's Health

    Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD.

  • Women's Health

    Women's Health

    Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD.

By clicking Submit, I agree to the WebMD Terms & Conditions & Privacy Policy

WebMD the app

Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

Find Out More
IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.