User Reviews for hydroxyurea oral

My platelet ct have been over 3 mil. where I was hospitalized and went through a gruling 3 days of 4 hours per day freezics. I am now on this drug 4 twice a day. My nails are brittle, my skin is turning dark, my hair is thinning and ever so often I get ghout like u want beleive. There is nothing else I can take for my problem mainly because I have high platelet and it is unknown why. Yes I've taken every test to include bone marrow and nothing. When my count is 1 million that is good for me.

I have been treated for Essential Thrombocytosis for several years. My platelet count keeps bouncing back and forth. Two months ago it was at the 500,000+ mark and this month at 900,000+. My Hemotologist keeps regulating the medication but finds it difficult to keep at a steady rate since lowering the platelet count affects my immune system. I have had bone marrow checks as well as numerous blood checks. I wish I (or my doctor) knew what to do.

condition being treated: high white blood platlets. side effects: stomach pain, dizzy, tired out, back pain, constipation to dihrea. problem - few alternatives.

Started taking Hydroxyurea 1500mg/day initially in Sept. 2006.  Had to decrease to 500mg/day within 2 months due to bone marrow toxicity and it lowered my neutrophils and white count precariously.  Saw a decrease in chronic bone pain within first 2-3 months of use, however still suffered 2 pain crises requiring hospitalization during that time.  I find this drug to only be moderately effective for my particular case of Sickle Cell Disease.  I have hemoglobin type SS with high F (or high fetal hemoglobin), which it will increase in those with low fetal hgb.  I already have a concentration of 22-23% fetal (F) and 77-78% sickle (S).  I only take it because it can help prevent other complications like acute chest, and seems to guards against organ damage as well as marked progression of Avascular Necrosis, which all can be increased with the number of vaso-occlusive/pain crises you experience.It makes me extremely fatigued.  Currently back on 1500mg/day (as of Nov. 2008) after 1 year of being on 500-1000mg on and off due to neutropenia.  Took a year-long break due to pregnancy.It does increase my hemoglobin after about 3 months of being on it consistently.  My baseline is between 9 and 10.  I have been up to 13 while on Hydroxyurea.  However, despite my hemoglobin being higher, I have still suffered long-lasting crises.  Its really a toss-up for me.  I especially worry about the risk of cancer after long-term use, which hasn't been well documented but the risk is still there.  Who knows just how long that "long-term use" is defined by?  Read More Read Less

this drug made every nerve ending in my body painful. it brought down the platette count but now my docotrr wants me to go on it agin for 90 days .

I have used Hydrea for over five years and also angrelide, both for an increase in blood platelets. I feel good but when the platelets count goes up, if seems like the hemaglobin count goes down. I am now getting Procrit for it right now. It is all based on the tests, but this is my observation of what happens. I also take angrelide for this condition

I have used Hydra for years now. My platelet count is watched bimonthly or monthly. I also take Agrylin with it twice a day. I am please with this treatment. Last month, I started on Procrit. I am not sure about this drug. Went today for a visit and did not need it.

the drug increased uric acid and have gout

dr. perscribed this medication because i have to many plates the above questions don't pertain because i don't know enough about the medication.

Initial 3years saw extreme decrease in vaso-occlusive crises then returned to frequent episodes annually. Stopped taking it for 4yrs and returned to normal dosage regimen of 1500mg/daily. No reductionin number of episodes but reductionin severity of crises. Used in conjuction with new drug not available in US yet (Hemoxin/Nicosan) and Hgb level steady at 9 and Hematocrit steady at 28. Worth itfor non child bearing individuals!

I take 500mg once a day for Essential thrombocytosis, I have been on it for four months and my platlets have gone from 1,200 to 404 I have sore joints but that is about it.