I have been taking Tenuate 75mg since November 2010, it says do not cut the pills, but I did, I cut them in 4, and started with 1/4 for a week or so, then up to 1/2 for a couple few weeks, and finally up to the whole pill. I take it very early, the minute I wake up, just before 6am. I have had no problem sleeping, do have the dry mouth, I drink a lot of water, which is good for you anyway. My doctor insists that I see a dietician evey month, plus I see him every month, he does not have refills on the RX, I get a new RX when I come to the monthly appt. My doctor says this is short-term, several months at the most. Also, the drug info that come with the RX at the pharmacy clearly says that nutritional counseling and exercise are to be used with this drug. I am following the dietician's instructions, that with the extra help from the Tenuate got me down 44lbs so far, 25 to go! This drug works great for me, and I have never taken diet pills before, other that OTC Dexatrim once when I was young. I am eating healthy, fresh foods, no sugar, no white flour, no processed foods, junk food at all. I am physically active also, not an exercise fanatic at all, just doing stuff all the time, and have a physical job. Read More Read Less