I week ago, I started an IT pump trial with Prialt. On the second, fourth, and fifth days after trial initiation, I returned to the pain center and the med was increased slowly (started out with about 4 mcg/day, increased eventually to about 7 mcg/day). With the first increase, my pain improved (decreased). With each successive increase of Prialt, my pain increased and so did side effects. I became extremely dizzy, nauseated (with vomiting), confused, lethargic, my vision blurred, and I was unable to do anything but lie in bed and wonder what Prialt was doing to my brain. I had to use a wheelchair for mobility, and it became difficult to understand what others were saying. I was unable to read as the appearance of words confused me, and I could not write legibly because my hands shook violently. I developed a headache that was unbearable, and my blood pressure skyrocketed (systolic >160, diastolic >110). On the sixth day, I could no longer stand the side effects and the increased pain and I turned the pump off. At this point in time, I have been off Prialt for 21 hours and I am slowly returning to normal. Earlier today, the catheter and external pump were removed and my doctor did not hesitate to say that Prialt was not for me. I am a very methodical and analytical person, but after all I had been through, my response was, "Ya think?????" I entered into this Prialt trial because like most long-term chronic pain sufferers, I have tried just about everything else (epidurals, physical therapy, massage, chiropractic, TENS, SCS, narcotic pain meds (HATE THEM), pump trials with morphine and dilaudid, exercising on my own, etc. Obviously, to voluntarily submit to a Prialt trial I felt a sense of desperation and that I was running out of options to live a life relatively free of pain. I pray that something effective and serious side effect-free will be developed and come on the market soon. For me, Prialt does not fit that description. Read More Read Less