User Reviews for Onglyza oral

I am not sure if the problems I'm having are from taking this drug. Started taking it about the same time I began having difficulty sleeping, dry mouth, lethargic, endema in legs and aching all over my body.

Maybe my review is a bit premature but I just started taking this medication last week. The day after I started taking it I began to feel extremely lethargic and began running a low-grade fever (99-100) off and on. Feeling bad in general. I take 1 Onglyza with 1 750 Metformin in the AM and then 1 Metformin 750 at night. My levels have come down some but not significantly enough where I'd like them. Maybe I just haven't given it time. I could just have a UTI or something but the coincidence is strange. Giving it a few more days and then I'm calling dr. I've lost about 18 lbs recently - don't have the sweet cravings mentioned but I have NO energy to exercise which is not good!Read More Read Less

I have daily headaches since starting this medication. I also have had intense cravings for sweets and have gained 5 pounds in the 7 weeks I have taken Onglyza.

Alert: Acute Lymphocyctic Leukemia - developed within 2 months after adding Onglyza to Meformin. (chance of ALL development in age group - 1 in 100,000). May 16, 2010 - Subject 55 yr old, healthy type 2 DM - Blood work WNL, Platelets of 258,000, Lymphs 25 %. May 26, 2010 - Onglyza added to Metformin. As of July 22, 2010 - Platlets: 36,000, Lymphs: 49%. Development of ACute Lymphocytic Leukemia (ALL). Suggest cautiona and close monitoring of CBC when adding Onglyza to Metformin.Per Bristol Meyers Squibb - in phase 3 study when Onglyza was added to Metformin - patient developed a " lymphoprolferative disorder" - type not specfied. The devlopment of Acute Lymphocytic Leukemia in 55 yr old type 2 DM (duration of DM x 2 years) reported to FDA Medwatch and reported to Bristol Meyer Squibb. Effect of Onlglyza on Lymph system not well described in prescribing information. Per Bristo Meyers Squibb - there was a dose -related mean decrease in lymphocyte count observed with Onglyza. Suggested lymhocyte count should be measured in setting of ususal or prolonged infection. More recent prescribing guidelines appear minimal and do not address changes in lymphs. Please research, review and monitor patients closely. Any acute leukemia development after adding Onglyza to Metformin? Any changes in Platelets/Lymps/CBC?PRead More Read Less

My sugar levels have come down, some since on Onglyza but I've had lower left side abdominal pain, every night and finally, noticed it is a symptom. I don't feel it is worth taking, with this pain and I've also noticed hair loss but could be from another med, I started near the same time. I am going off it and hope to find something that lowers without causing a worse problem. None of this was explained to be, prior to my starting Onglyza. Would NOT recommend! Worried about this pain. Never had it before and also, I've felt very warm in the mornings. Read More Read Less

severe stomach cramps and gas, stomach distended and hard.

Taking since 3-1, my blood levels are not spiking anymore. Very pleased as all my meds have been drastically reduced. Losing weight, but working really hard on a lifestyle change in that area. AM readings 110 instead of 165...

I just took one at noon and will see how it does. Person who took at bedtime - doctor's order. I would be afraid to take it then for fear of night lows which may be occurring. I take 120 mg Starlix before each meal and see if it will be necessary with the new.

Have noticed alot of water retention and extreme fatigue. Also trouble sleeping and feel VERY warm in the a.m. I take at night, helped more in the first few wks now seems my a.m. blood sugar is climbing again.

have been having very bad headaches with the med but it does lower my sugar levels. I not sure I wish to continue with it because of the pain in my head even with taking advil

I take 2 metformin 500 ER pills every night and one 5mg onglyza and my numbers had dropped dramatically from 154 to 118 after using onglyza for 2 weeks along with Metformin.

Numbers are down to normal or near normal range. No noticeable adverse side effects. I was diagnosed in 1990 and was treated for two years, lost several pounds and quit taking glucotrol. Recently had a TIA and was put on onglyza. After two weeks numbers were in normal range again. Expensive but my insurance is good so far.

A bone spur forms as the body tries to repair itself by building extra bone. Am now wondering if this is the side effect for the lumps on my legs.

Have taken for 4 weeks and has lowered sugar readings so I like it. But today am seeing lumps on bones.. around knee cap and ankles and top of left leg bone near foot. not sure what these are and now leg cramps this morning. Will check with doc on bone lumps.

Can't say it is working very well for me; but have noticed I'm having more headaches and a ridiculously high craving for sweets. I think I was better off without the Onglyza.

I am having dry mouth and sweating at night. Not lowering my glucose as much as it probably should.

I, too, have had night sweats but didn't relate it to the medicine until I read the other reviews. My insurance won't pay for it so it is quite expensive. It has not helped with lowering my blood sugar.

After being on the medication for a couple of days I noticed drenching night sweats and a rise in my B/P due to retaining of water. I've tried to start this med twice with the same results. Also sever leg cramps. Will not take it again.

Since starting onglyza my blood sugars are lower in AM, I use less insulin during the day, less lantus at bedtime . Cost is ridiculously high.Only side effect for me is morning leg cramps 3-4 times a week.

I was very close to having full blown diabetes. Onglyza, a change in diet and exercise, have shown a significant improvement.