Show ratings & reviews for

3.6 Overall Rating

Effectiveness

Ease of Use

Satisfaction

Most voted positive review

65 People found this comment helpful

I am just finishing my treatment-first two years on tamoxifen but switched to letrozole after experiencing muscle spasms + cramps. 3 years on letrozole and at first experienced very bad joint pain which lasted about 1 year but did wear off, and not noticable at all now. All the way through the treatment quite bad hot flashes (different levels from plain hot sweats to hot sweats with panic attacks...

Most voted negative review

9 People found this comment helpful

I have just recently been switched from Femara to Letrozole (I am certain cost was a major factor in this decision). This is just the first month I am on Letrozole so it is really too early to tell the outcome.

Shared reviews and ratings

Gerrior38 | 55-64 | Female | On medication for 1 to 6 months | Patient
12/17/2019
Condition: Hormone Receptor Positive Postmenopausal Early Breast Cancer
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I've been on Letrozole for 3 months, and I have flu like symptoms daily,nausea and vomiting also constipation. But the worst symptom is No sleeping, and my brain is foggy. I've stopped taking this, haven't told my Oncologist yet!! My legs are very slow to steady causing severe dizziness.

Report this postFill 3Created with Sketch.
Ashley | 25-34 | Female | On medication for less than 1 month | Patient
9/24/2019
Condition: Infertility associated with the Lack of Ovulation
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Took this drug days 3-7 and now I am 9 weeks pregnant ????. Crazy it only took one time on these and they helped! We were trying for over a year without help.

Report this postFill 3Created with Sketch.
Connie | 55-64 | Female | On medication for 1 to 6 months | Patient
5/11/2019
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I also am experiencing severe joint pain, bone pain, numbness and tingling in hand, hand joints throbbing, and a rash on many areas of my body. After I stand up from sitting a while, I can't seem to walk well. It takes a while to stop shuffle walking and stooped over to correct posture and normal steps.

Report this postFill 3Created with Sketch.
Anonymous | 55-64 | On medication for 1 to 6 months | Patient
5/11/2019
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

6 years ago I started tamoxifen, after the first 2 years I could barely walk, the joint pain was awful, even had to sell my stick shift car. Finished the 5 years with aremidex. Within few months all the pain was gone. Got breast cancer back, now on letrozole. My doctor started me on cymbalta for 3 weeks first, she has had success with cymbalta decreasing the joint pain. Iâ??m optimistic that it will help. Good luck to everyone taking here drugs!

Report this postFill 3Created with Sketch.
Anonymous | 65-74 | On medication for 2 to less than 5 years | Patient
1/1/2019
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I have been on Letrozole for approx 2 3/4 yrs with varying side effects (depending on lot number), but the constant side effect has been the destruction of my joints, connective tissue, and mobility! A recent bone scan has indicated the same. It's progressively worse

Report this postFill 3Created with Sketch.
JDon | 65-74 | Female | On medication for 6 months to less than 1 year | Patient
12/27/2018
Condition: Hormone Receptor Positive Postmenopausal Early Breast Cancer After Adjuvant Tamoxifen
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

Started taking Letrozole in May 2018. I have been getting many migraine visual auras which make me feel weird and out of it--I hate it. I have mild shoulder and hip pain that I can tolerate. I have an irregular heartbeat which I am fairly sure the drug is making worse. I have stopped taking it to see if my pulse slows down to a more normal rate. Has anyone else experienced an increase in heart rate?

Report this postFill 3Created with Sketch.
Lynzy | 45-54 | On medication for 1 to 6 months | Patient
10/29/2018
Condition: Breast Cancer that has Spread to Another Part of the Body
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

This medication created a life in 2 months on oxygen, pain to breath and corotid artery disease. I never had high cholesterol, fact is my colesterol was excellent. Letrozole created a plaque in a few days that clogged my artery. Surgeon never saw anything like the goop he pulled out with no signs of this disease in the artery. This was in 2014, I am allergic anastozol and had to research other meds. I could bearly walk and couldn't hold anything in my hands. I have recently met 6 people over the last 4 months with similar issues and results reported get ignored. Read More Read Less

Report this postFill 3Created with Sketch.
JoanS | 55-64 | Female | Patient
10/20/2018
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I started taking this medicine in June. I am currently experiencing most of the unpleasant side effects. Worst being joint aches, fatigue, hot flashes, mood swings and hair thinning. Thankfully, I am not gaining weight. Without yoga and acupuncture, I do not know if I could tolerate this medicine. Good luck to anyone out there taking it!

Report this postFill 3Created with Sketch.
JG | 65-74 | On medication for 2 to less than 5 years | Patient
7/25/2018
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I have been taking this for 2 years now and everything was good until lately. I have a lot of the same things going on as the others. Mostly muscle soreness, joints, tired, trigger finger on both hands, hard to walk when I first stand up until my legs relax. I will continue to take it because I don't want my cancer to come back.

Report this postFill 3Created with Sketch.
S.B | 45-54 | On medication for 1 to less than 2 years | Patient
7/19/2018
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I have been on letrolzole oral for 13 months now. At first I didn't really have any problems, but the more I take it the more problems I have. I started out with severe loss of appetite. I've lost around 40 pounds since starting it. Right after I hit the year mark, I've started having severe insomnia. My doctor has tried everything to help me sleep but nothing has worked. I don't know how much longer I can take it. My diagnoses was lobular carcinoma insitu with microinvation, which was 7mm, the size of a pencil lead. I don't know whether I should keep taking it or not. I don't think I can take much more of the insomnia. Read More Read Less

Report this postFill 3Created with Sketch.
Anonymous | 55-64 | Female | On medication for less than 1 month | Patient
7/5/2018
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I have just been on for a week. I use to be on Arimdex but hot flashes became so severe I had to stop it. I decided not to take anything for a couple of y ears and now doctor said try this one. I did find out by my radiation doctor that if I take magnesium OTC every day that would stop hot flashes. She was right from day one they stopped it. I took 250 mgs a day every week for a month and they helped tremendously so then I cut it down to 3 times a week. For those of you taking this med remember magnesium can greatly decreased hot flashes. You do not need RX for it you can find it in vitamins isle.Read More Read Less

Report this postFill 3Created with Sketch.
Brenda57 | 55-64 | On medication for 1 to 6 months | Patient
5/14/2018
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

started day after radiation ended. within first week all 10 joints of fingers started hurting and feeling hot. tried playing piano to keep fingers active. doesn't help. After 2 months, surgeon said to stop and let oncologist put me on something else. I've been directed to give this time to clear out and start exemestane for a 2nd chance. could do tamoxifen or take nothing at all if none of these work. my cancer was caught early with a 3d mammoth and had not spread to nodes, just invasive ductal. I was super lucky but always get annual mammograms since I was 40. My mom had it so I have been proactive watching out for it.Read More Read Less

Report this postFill 3Created with Sketch.
birdlady | 65-74 | Female | On medication for 6 months to less than 1 year | Patient
5/6/2018
Condition: Hormone Receptor Positive Postmenopausal Early Breast Cancer
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

I have been on Letrozole for 10 months now. At first I had alot of neck pain, very painful! went to several Drs. for it,they can't do any thing but physical therapy and trigger point inj. which makes things worse,tried both. so I go back to see what side effects others are having and guess what they have knee ,wrist, neck and hip pain also. Currently it is knee pain ,limits my walking and wakes me up at about 3am, very painful. I bought a knee brace which helps if I plan on walking far. Any suggestions ? When I tell the drs. this, they look at you like your requesting Cocaine or something. I just want pain relief and to sleep good without pain !! Read More Read Less

Report this postFill 3Created with Sketch.
LA | 45-54 | On medication for 2 to less than 5 years | Patient
1/29/2018
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

I have been on letrozole for almost 5 years. The joint pain in my knees has never gone away. Stiffness is normal; especially in my legs. Weakness in my legs is worsening. Fingers and feet stiff and numb too. Hot flashes when I exert myself with simple tasks. Doctor would like me to continue beyond 5 years but doctor allowing me to take 2 to 3 months off. Hope I will feel better during the break in treatment.

Report this postFill 3Created with Sketch.
Mary | 65-74 | On medication for 10 years or more | Patient
1/19/2018
Condition: Breast Cancer that has Spread to Another Part of the Body
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I have been on this med for 15 years. I had no trouble until I switched pharmacies. Now I have some hair loss and many of the symptoms associated with menopause. I am 70 so menopause should be in the rear view mirror. I suspect that there must be a different manufacturer or some difference with a new pharmacy.

Report this postFill 3Created with Sketch.
demon pill | 55-64 | On medication for 6 months to less than 1 year | Patient
11/1/2017
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

Taking letrozole for 6 months I had no side affects at all, then the muscle aches, and joint pains started and also put me right back into menopause, with severe hot flashes...Aches and pains stop when i sit down and take a break, hot flashes have also mellowed out a bit, I have been taking this medication now for 9 months. Almost afraid to change meds, hearing how others are affected all these things may mellow, and all pills have side affects...Gained a little weight but now that is stablizing and have lost weight..Read More Read Less

Report this postFill 3Created with Sketch.
Martha | 55-64 | On medication for 2 to less than 5 years | Patient
10/16/2017
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

This is my third medication since finishing cancer treatments. Others delivered severe side effects. Still suffer some hot flashes, fatigue. But growing used to these symptoms. Body aches are constant: muscle and joint pain, stiffness in hips and legs. Building tolerance to pain, and keep prescriptionn pain killer on hand for occasional use. Daily walks, stretches, tai chi help greatly. Staying active also good for blood circulation and mental well-being. Only 2 1/2 years left!

Report this postFill 3Created with Sketch.
Sue | 45-54 | On medication for 6 months to less than 1 year | Patient
10/15/2017
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I have been on Letrozole for about 8 months now. Doc says we are doing the 5 year at a time plan. When I first went on it I had insane issues. I had extreme memory issues and brain frog, extreme low energy, I would fall over for no reason while walking. Within about 8 weeks those symptoms mellowed completely out and have gained serous joint and muscle issues. Mostly in my fingers and hips but thatâ??s ok. Some days I feel 80 not 50 but I am more then willing to put up with a few aches though if it means I get to live a full life.Read More Read Less

Report this postFill 3Created with Sketch.
Ammu | 25-34 | Female | On medication for less than 1 month | Patient
9/20/2017
Condition: Stimulation of Ovarian Function
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

I tried for this medication only one month but not able to follow the dates to conceive my bad luck . It induced my period on time which near happened with clomid

Report this postFill 3Created with Sketch.
Sherry | 55-64 | On medication for 1 to less than 2 years | Patient
9/10/2017
Condition: Cancer of the Ovary
Overall rating 4.3
Effectiveness
Ease of Use
Satisfaction

I have been on this drug for 15 months. I have joint pain in all my joints but much worse in my elbows, wrists and hands. I had steroid shots in 7 of my fingers to relieve the pain. I have stage 3 ovarian cancer and this drug has helped keep me in remission. I will be on the drug for another 9 months. My symptoms get worse, the longer that I am on the drug but I am thankful that the drug is working to my benefit to keep the cancer from returning. I do have a lot of fatigue and pain, almost like the symptoms of my cancer. It is hard to make a fist with my hands because they are stiff and swollen. My elbows are in constant pain and I have muscle aches from my shoulders to my wrists. I take a Tylenol arthritis medicine twice a day to help. I like the purpose of this drug but it does weigh you down mentally and physically. But I will keep taking it because I am alive!Read More Read Less

Report this postFill 3Created with Sketch.

IMPORTANT INFORMATION ABOUT USER-GENERATED CONTENT ON WEBMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions.

Read More