Show ratings & reviews for

3.4 Overall Rating

Effectiveness

Ease of Use

Satisfaction

Most voted positive review

12 People found this comment helpful

My entire body hurts all the time and I am always tired

Most voted negative review

1 People found this comment helpful

Wasn't able to continue Tamoxifen due to side effects, and wasn't postmenopausal yet. My MD recommended an Aromatase Inhibitor with the Zoladex. I was afraid of some of the side effects listed, but agreed to try. I have been on this regimen for 9 months now. The bone and joint pain and inflammation of tendons is becoming unbearable. Have read lots of journals that describe the long lasting effects...

Shared reviews and ratings

Anonymous |
2/28/2024
Condition: Other
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

ZOLADEX leading up to my major operation to remove those dreadful fibroids, i was injected with ZOLADEX for three months leading up to the month i had the operation. It did not shrink the fibroids, all it did was to put me through unnecessary hot flushes, sweating and confusion. Horrible dreadful nasty experience which i would not wish on anyone. I was having a regular monthly cycle and no hot flushes. I also went through hell after the operation. I scream in pain as thr nurse removed one of the two tubes feom my tummy. I mentioned this to her and nothing was done. I had the operation on monday and i was sent out on friday within five days. That same driday night my body was on a tremor, with sweating and having a temperature. The cel doc arrived and asked me to do a urine sample, he then said i have all the colours of the rainbow on his test strip. The doctor said i have a kidney infection. This cleared up. I could go on and on but this will take all day. I HATE HOSPITAL, and very frighten of hospital. When i complained to the stupid non caring nurse that i felt unwell and screaming in pain when she removed one of my tubes should have told her something was wrong. I left hospital with kidney infection which should not hsve happened. Recovery period was not easy.Read More Read Less

Report this postFill 3Created with Sketch.
Nadia | 19-24 | Female |
2/26/2024
Condition: Endometriosis
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I was 23 when I was given a course of this medication, I’m now 46, with a lifelong history of sexual dysfunction which to date has not recovered. I’m a female and was prescribed this in the U.K. to treat Fibroids, prior to surgery, however the medication stole my sex drive. I was in a relationship at the time, which resulted in my boyfriend leaving me, additionally many hospital and GP visits in an attempt to recover my sex drive, with no success - I have tried everything.. this medication has ruined my life for ever. Read More Read Less

Report this postFill 3Created with Sketch.
Lou | 45-54 | Female | On medication for 6 months to less than 1 year | Patient
2/8/2023
Condition: Other
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

I was put on Zoladex to stop periods prior to hysterectomy due to fibroids. I wish I had never started it. I bled non stop for months and started with high blood pressure. I have never felt as ill. Because of non stop bleeding I ended up anaemic and my hysterectomy was cancelled. I have stopped having the implants but symptoms have stayed with me and I can get no help to solve this problem.

Report this postFill 3Created with Sketch.
Sonya | 45-54 | Female | On medication for less than 1 month | Patient
1/3/2023
Condition: Other
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I am 50. I have a 9cm fibroid that didn't give me any symptoms. My gynaecologist suggested that I needed to get the fibroid size down so I took one injection. My fibroid didn't shrink. In fact, I now have a 9cm Fibroid and a new one. I had almost every symptom, from raised sugar blood levels (I was told I was nearly prediabetic after taking zoladex), to high calcium levels in my blood. I could hardly walk - every bone creaked and brought me pain. I had dizziness and raging headaches. I only had one month of Zoladex but it has left me with a front heas headache that is with me most days requiring panadol. I am left with violent, frequent flashes which I have been told are more intense than natural ones. I never had joint ache or bone aching before taking Zoladex nor the front forehead headaches. I am concerned that people are being prescribed Zoladex for pain relief for edometrosis when it affects your bones, can give you osteoporosis and diabetes. If I could go back in time, I would have ran a mile away from this horrid, horrid medication that made me so sick that I couldn't get out if bed for an entire month. NO I DO NOT RECOMMEND ZOLADEX FOR A FIBROID IF YOU DONT NEED AN OPERATION.Read More Read Less

Report this postFill 3Created with Sketch.
Mike Stephen | 75 or over | Male | On medication for 1 to less than 2 years | Patient
8/18/2022
Condition: Cancer of the Prostate Gland
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

After a number of treatments the latest has almost killed me. I am breathless to the point of being unable to move other than extremely slowly, I now have heart irregularity - symptoms requiring treatment and, even though these serious side effects are in the pharmacy and Cancer Agency information, my urologist will not even come out of his office to discuss, just sends out a message that it isn’t the Zoladex!

Report this postFill 3Created with Sketch.
anonymous | 55-64 | Male | On medication for 1 to less than 2 years | Patient
5/15/2022
Condition: Cancer of the Prostate Gland
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Had Prostatectomy (Robotic) and I am on Zoladex now as my PSA started rising a little, but yet not within detectable range (0.017). As a precaution my Urologist recommended an Preventive Salvage Radiation and put me on additional Zoladex for 2 Years. I agreed absolutely, early Intervention the better the chances of cure. Almost done now with Zoladex ( 2 Injections more to come). I have NO side effects whatsoever and feel great. PSA down <0.003 (Machine limit). Very effective.

Report this postFill 3Created with Sketch.
Anonymous | 35-44 | Female | On medication for 1 to 6 months | Patient
5/2/2022
Condition: Endometriosis
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

After bleeding for 2 years straight and severe pain for majority of the time I feel Zoladex was a life changer I have severe Hot flushes, bad headaches, forgetfulness, low libido, whole body aches, I sleep very little, & can have mood swing but I will take all of these symptoms over bleeding all the time and being in severe pain. I have just had my 5th out of 6 and I don't even find having the injection that bad

Report this postFill 3Created with Sketch.
SB Jaipur | 19-24 | Female | On medication for 1 to 6 months | Patient
4/14/2022
Condition: Additional Destruction of the Inner Wall of the Uterus
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

My wife was given zoladex 3.6 after 2 dose she is suffering from varicose veins in legs I really pray that her heart veins are not damaged. We have stopped the treatment this drug should be banned for other then cancer use. My wife was advised for HRT for preparation for IVR however we regret going to doctor who advised us a cancer drug and spoiled my wife’s veins and legs…

Report this postFill 3Created with Sketch.
Julie | 19-24 | Female | On medication for 1 to 6 months | Patient
1/13/2022
Condition: Endometriosis
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

I am 3 months through my treatment on Zoladex and though has completely eliminated the pains, cramps, vomiting and irregular bleeding due to my endometriosis and adenomyosis, it has been so hard. I've been experiencing hot flashes, high anxiety levels, insomnia, mood swings, weight gain, constantly feeling tired and low libido. It has made me feel so emotional and insecure, but I know and understand that these are short term problems for something that will help me so much in the long term. So I will wait it out as I feel I can handle these side effects for another 3 months.Read More Read Less

Report this postFill 3Created with Sketch.
Cametted | 35-44 | Female | On medication for 10 years or more | Patient
10/12/2021
Condition: Hormone Receptor Positive Breast Cancer
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

I'm on Zoladex and Tamoxifen been on the shot for 9 months at first it was horrible I was nauseous, severe headaches, bone pain. I am type 1 diabetic so bood sugars go out of control the week I have the injection. Side effects are easing up but still have headaches her and there. If the stops my reoccurrence of cancer. Then I'll stick to it!

Report this postFill 3Created with Sketch.
Stef | 45-54 | Male | On medication for 1 to 6 months | Patient
10/8/2021
Condition: Cancer of the Prostate Gland
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

Anxiety,hot flashes,insomnia,high blood preasure.depression,fatique and headache,sex libido almost zero.I am not going to take the second shot its a nightmare!!

Report this postFill 3Created with Sketch.
Me | 35-44 | On medication for 1 to 6 months | Patient
7/1/2020
Condition: Endometriosis
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

In the beginning, this medication was awful. I had severe headaches, dizzy spells, feeling nauseous, and severe menstrual bleeding for the first three weeks. But now, after being on it for over a month, those symptoms have decreased and I feel more relieved. The only two complaints that I have right now are SERIOUS HOT FLASHES AND MUSCLE PAIN at its finest! If I could rid of those two side effects, I’d b a happy camper!

Report this postFill 3Created with Sketch.
Jonah Hughes | 13-18 | Male | On medication for 1 to less than 2 years | Patient
11/21/2019
Condition: Other
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

This drug has helped me be a boy when i was unhappy as a girl. As i am only 13 the needle is big a still hurts quiet a bit and the side effects are annoying but it stops my period and my boobs from growing. it has though created a reflex for me when ever someone tries to touch me near the stomache

Report this postFill 3Created with Sketch.
Katherine | 45-54 | On medication for 6 months to less than 1 year | Patient
10/7/2018
Condition: Breast Cancer
Overall rating 2.7
Effectiveness
Ease of Use
Satisfaction

Wasn't able to continue Tamoxifen due to side effects, and wasn't postmenopausal yet. My MD recommended an Aromatase Inhibitor with the Zoladex. I was afraid of some of the side effects listed, but agreed to try. I have been on this regimen for 9 months now. The bone and joint pain and inflammation of tendons is becoming unbearable. Have read lots of journals that describe the long lasting effects due to permanent changes in the brain, basically lowering the pain receptor threshold. I'm worried that I have traded one life altering event for one just as devastating. Read More Read Less

Report this postFill 3Created with Sketch.
Zzzzz | 25-34 | Female | On medication for 1 to 6 months | Patient
4/30/2018
Condition: Endometriosis
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I don’t usually leave reviews but I felt this was important to because there are so many unpleasent experiences written about this drug, but on balance I can honestly say it’s not that bad. I did not want to take Zoladex after reading up on it, I was very nervous of the side effects and I reluctantly started monthly injections for 4 months in preparation for surgery. The actual injection it’s self did hurt, but it gets slightly better each month. My first injection left a small bruise but none after that. It stopped my periods which for me was a huge relief not having to deal with so much pain each month. I didn’t get any side effects for about 3 weeks and I did notice about a week before each injection I was getting a little pain, which soon settled after my injection again. Side effects - hot flushes, sweaty and hot at night, difficulty falling asleep then tired in the mornings and muscle aches. Which doesn’t sound great but apart from the hot flushes not each of these side effects were daily. Short term it’s annoying but long term if it’s going to help prep for surgery and give you a better surgical result then it’s totally worth it in my opinion. I suffered no spots (which I was expecting as my skin can be bad) and no weight gain. Read More Read Less

Report this postFill 3Created with Sketch.
Harold | 75 or over | Male | On medication for less than 1 month | Patient
12/6/2016
Condition: Cancer of the Prostate Gland
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

After 6 months of the subcutaneous injection, I (MALE) have severe breast pain and swelling plus my PSA has increased from 2.9 to 7.3 ? I am not too happy with this drug.

Report this postFill 3Created with Sketch.
Anonymous | 25-34 | Female | On medication for 1 to 6 months | Patient
11/23/2015
Condition: Endometriosis
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

This is my 3rd lot of zolidex, I had it first to control my endo, (19 years old), then before I had a tcre , (26 years) which has now failed after 3 years it's growing back and now on it again whilst I wait for a hystorectomy, (30 years) i do get painfull stiff joints, hair loss and bad hot flushes but wouldn't change that for the pain and bleeding without being on it ??

Report this postFill 3Created with Sketch.
Anonymous | 65-74 | Male | Patient
9/6/2014
Condition: Advanced Form of Prostate Cancer
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I think this product should be taken off the market, I first took this product as therapy for prostate cancer. in 2007, neither the VA doctor nor the nurse who administered this offered any info on side effects. long term side effects are this drug had the effect of reducing my testosterone alright by completely eliminating my testicals the source of testosterone, I've been casterated. I have no, nuts, to say it crudely. I have no body hair and have continusly gained weight over the years, I have no sex drive and I am now impotent and have been since fist administered in 2007, no motivation,no ambition, "quality of life very bad without testosterone. if I could sue someone I would, did it help with the prostrate cancer? don't know my PSA is <.01 so that's good Read More Read Less

Report this postFill 3Created with Sketch.
Combat Vet | 55-64 | Male | On medication for 5 to less than 10 years | Patient
11/7/2013
Condition: Advanced Form of Prostate Cancer
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I am a Vietnam Veteran, I had a PSA of 58.5 and the cancer had spread outside the prsotate. after radiation of 45 days I was put on Zoladex and will be for the rest of my life to control the cancer. I believe this drug has saved my life. I have hot flashes but I can take that to know my cancer is being treated.

Report this postFill 3Created with Sketch.
Anonymous | 45-54 | Female | On medication for 1 to 6 months | Patient
7/5/2013
Condition: Breast Cancer that has Spread to Another Part of the Body
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I have been taking it for only 5 months. I experienced a few side effects at first, such as nausea and headaches. So far, no other problems has developed.

Report this postFill 3Created with Sketch.

IMPORTANT INFORMATION ABOUT USER-GENERATED CONTENT ON WEBMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions.

Read More