Changes to This Summary (03 / 01 / 2013)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Description of the EvidenceUpdated statistics with estimated new cases and deaths for 2013 (cited American Cancer Society as reference 1).This summary is written and maintained by the PDQ Screening and Prevention Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.
Cellular Classification of Malignant Mesothelioma
Histologically,these tumors are composed of fibrous or epithelial elements or both. The epithelial form occasionally causes confusion with peripheral anaplastic lung carcinomas or metastatic carcinomas. Attempts at diagnosis by cytology or needle biopsy of the pleura are often unsuccessful. It can be especially difficult to differentiate mesothelioma from adenocarcinoma on small tissue ...
Description of the Evidence
BackgroundIncidence and mortalityLung cancer is the most commonly occurring noncutaneous cancer in men and women combined in the United States and is the leading cause of cancer deaths. In 2013 alone, it is estimated that there will be 228,190 new cases diagnosed, and 72,220 women and 87,260 men will die from this disease. The lung cancer death rate rose rapidly over several decades in both sexes, with a persistent decline for men commencing in 1991. From 2005 to 2009, death rates decreased by 2.8% per year in men and by 1.0% per year in women.Risk factorsTobacco use, second hand smoke, and other risk factorsThe most important risk factor for lung cancer (as for many other cancers) is tobacco use.[2,3] Cigarette smoking has been definitively established by epidemiologic and preclinical animal experimental data as the primary cause of lung cancer. This causative link has been widely recognized since the 1960s, when national reports in Great Britain and the United
Treatment Options for Recurrent Small Cell Lung Cancer
Treatment of recurrent small cell lung cancer may include the following: Radiation therapy as palliative therapy to relieve symptoms and improve quality of life. Chemotherapy as palliative therapy to relieve symptoms and improve quality of life. Laser therapy,surgical placement of devices to keep the airways open,and/or internal radiation therapy,as palliative therapy to relieve symptoms and ...
Recurrent Small Cell Lung Cancer Treatment
Standard Treatment Options for Patients With Recurrent Small Cell Lung Cancer (SCLC) Standard treatment options for patients with recurrent SCLC include the following: Chemotherapy. Palliative therapy. At the time of recurrence,many SCLC patients are potential candidates for further therapy. Chemotherapy Although second-line chemotherapy has been shown to produce tumor regression,responses ...
Treatment Option Overview for NSCLC
In NSCLC,results of standard treatment are poor except for the most localized cancers. All newly diagnosed patients with NSCLC are potential candidates for studies evaluating new forms of treatment. Surgery is the most potentially curative therapeutic option for this disease. Postoperative chemotherapy may provide an additional benefit to patients with resected NSCLC. Radiation therapy ...
The only reported adverse effect with the use of Selected Vegetables/Sun’s Soup was a feeling of fullness or bloatedness when DSV was consumed in the amount specified in the phase I/II clinical trial.[ 1 ] No adverse effects were reported after ingestion of FSV.[ 2 ] References: Sun AS,Ostadal O,Ryznar V,et al.: Phase I/II study of stage III and IV non-small cell lung cancer patients taking a ...
Stages of Non-Small Cell Lung Cancer
After lung cancer has been diagnosed,tests are done to find out if cancer cells have spread within the lungs or to other parts of the body. The process used to find out if cancer has spread within the lungs or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan ...
Questions or Comments About This Summary
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Advanced Malignant Mesothelioma (Stages II, III, and IV)
STANDARD TREATMENT OPTIONS: Symptomatic treatment to include drainage of effusions,chest tube pleurodesis,or thoracoscopic pleurodesis.[ 1 ] Palliative surgical resection in selected patients.[ 2,3 ] Palliative radiation therapy.[ 4,5 ] Single-agent chemotherapy. Partial responses have been reported with doxorubicin,epirubicin,mitomycin,cyclophosphamide,cisplatin,carboplatin,and ...