Treatment Options for Recurrent Small Cell Lung Cancer
Treatment of recurrent small cell lung cancer may include the following: Radiation therapy as palliative therapy to relieve symptoms and improve quality of life. Chemotherapy as palliative therapy to relieve symptoms and improve quality of life. Laser therapy,surgical placement of devices to keep the airways open,and/or internal radiation therapy,as palliative therapy to relieve symptoms and ...
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Changes to This Summary (03 / 01 / 2013)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Description of the EvidenceUpdated statistics with estimated new cases and deaths for 2013 (cited American Cancer Society as reference 1).This summary is written and maintained by the PDQ Screening and Prevention Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.
Cellular Classification of Malignant Mesothelioma
Histologically,these tumors are composed of fibrous or epithelial elements or both. The epithelial form occasionally causes confusion with peripheral anaplastic lung carcinomas or metastatic carcinomas. Attempts at diagnosis by cytology or needle biopsy of the pleura are often unsuccessful. It can be especially difficult to differentiate mesothelioma from adenocarcinoma on small tissue ...
Stage 0 NSCLC Treatment
Stage 0 NSCLC frequently progresses to invasive cancer.[1,2,3] Patients may be offered surveillance bronchoscopies and, if lesions are detected, potentially curative therapies.Standard Treatment Options for Stage 0 NSCLCStandard treatment options for stage 0 NSCLC include the following:Surgery.Endobronchial therapies, including photodynamic therapy, electrocautery, cryotherapy, and Nd-YAG laser therapy.SurgerySegmentectomy or wedge resection are used to preserve maximum normal pulmonary tissue since patients with stage 0 NSCLC are at a high risk for second lung cancers. Because these tumors are by definition noninvasive and incapable of metastasizing, they should be curable with surgical resection; however, such lesions, when identified, are often centrally located and may require a lobectomy. Endobronchial therapiesPatients with central lesions may be candidates for curative endobronchial therapy. Endobronchial therapies that preserve lung function include photodynamic therapy,
Limited-Stage Small Cell Lung Cancer Treatment
Standard Treatment Options for Patients With Limited-Stage Small Cell Lung Cancer (SCLC) Standard treatment options for patients with limited-stage SCLC include the following: Chemotherapy and radiation therapy. Combination chemotherapy alone. Surgery followed by chemotherapy or chemoradiotherapy. Prophylactic cranial irradiation. Chemotherapy and radiation therapy Combined-modality treatment ...
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Stage Information for Malignant Mesothelioma
Patients with stage I disease have a significantly better prognosis than those with more advanced stages. Because of the relative rarity of this disease,exact survival information based upon stage is limited.[ 1 ] Definitions of TNM The American Joint Committee on Cancer has designated staging by TNM classification to define malignant mesothelioma.[ 2 ] International Mesothelioma Interest Group ...
Stages IA and IB NSCLC Treatment
Standard Treatment Options for Stages IA and IB NSCLCStandard treatment options for stage IA NSCLC and IB NSCLC include the following:Surgery.Radiation therapy.Chemotherapy and radiation therapy have not been shown to improve outcomes in stage I NSCLC that has been completely resected.SurgerySurgery is the treatment of choice for patients with stage I NSCLC. A lobectomy or segmental, wedge, or sleeve resection may be performed as appropriate. Patients with impaired pulmonary function are candidates for segmental or wedge resection of the primary tumor. Careful preoperative assessment of the patient's overall medical condition, especially the patient's pulmonary reserve, is critical in considering the benefits of surgery. The immediate postoperative mortality rate is age related, but a 3% to 5% mortality rate with lobectomy can be expected.Evidence (surgery):The Lung Cancer Study Group conducted a randomized study (LCSG-821) that compared lobectomy
Treatment Option Overview
Standard treatment for all but localized mesothelioma is generally not curative. Although some patients will experience long-term survival with aggressive treatment approaches,it remains unclear if overall survival has been significantly altered by the different treatment modalities or by combinations of modalities. Extrapleural pneumonectomy in selected patients with early stage disease may ...